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Fig. 3 | Cardiovascular Diabetology

Fig. 3

From: SGLT2 inhibition with empagliflozin attenuates myocardial oxidative stress and fibrosis in diabetic mice heart

Fig. 3

Empagliflozin suppresses matrix accumulation and myocardial fibrosis in DM mice. Immunostaining of TGF-β1, collagen I and collagen III protein expression and Masson’s trichrome staining of the myocardium (a). The percentages of positive areas of TGF-β1 (b), collagen I (c), collagen III (d) and connective tissue fraction (e). Data are expressed as the mean ± SD. *P < 0.05 vs. Con; #P < 0.05 vs. DM

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