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Table 6 Metabolite ratios correlated with blood lipids and serum Hp levels in non-DM subjects

From: Association between serum haptoglobin and carotid arterial functions: usefulness of a targeted metabolomics approach

Metabolite ratios

Total cholesterol

Triglycerides

HDL-C

LDL-C

Serum Hp

Carotid IMT

Asp/PC ae C32:2

0.028 ± 0.538

− 0.072 ± 0.101

− 0.605 ± 0.220

− 0.254 ± 0.315

0.048 ± 0.015

0.362 ± 0.206

0.9592

0.4748

0.0071

0.4212

0.0012

0.0820

Glu/PC ae C32:2

− 0.830 ± 0.584

0.020 ± 0.109

− 0.442 ± 0.239

0.317 ± 0.342

0.043 ± 0.016

0.386 ± 0.223

0.1585

0.8514

0.0673

0.3559

0.0071

0.0870

Phe/PC ae C32:2

− 0.311 ± 0.407

− 0.052 ± 0.076

− 0.493 ± 0.167

0.062 ± 0.238

0.029 ± 0.011

0.351 ± 0.156

0.4470

0.4945

0.0039

0.7948

0.0094

0.0267

  1. Multiple linear regression analysis was used to perform the analysis after adjusting for age, sex and body mass index with total cholesterol, triglycerides, HDL-C, LDL-C, serum Hp level tertiles and carotid IMT as independent variables. β ± SE and P values are shown in table
  2. Non-DM non-diabetes mellitus, Asp aspartate, Glu glutamic acid, Phe phenylalanine, Hp haptoglobin, HDL-C high-density lipoprotein-cholesterol, LDL-C low-density lipoprotein-cholesterol, IMT intima-media thickness
  3. P values < 0.05 or approximately 0.05 are shown in italic