|
Metabolite ratios
|
Total cholesterol
|
Triglycerides
|
HDL-C
|
LDL-C
|
Serum Hp
|
Carotid IMT
|
Carotid IAD
|
|---|
|
Asn/PC ae C32:2
|
− 0.949 ± 0.290
|
0.061 ± 0.066
|
− 0.006 ± 0.137
|
0.277 ± 0.164
|
0.033 ± 0.012
|
0.344 ± 0.114
|
− 0.230 ± 0.196
|
|
0.0015
|
0.3555
|
0.9626
|
0.0942
|
0.0059
|
0.0032
|
0.2433
|
|
Asp/PC ae C32:2
|
− 0.723 ± 0.367
|
0.047 ± 0.083
|
− 0.153 ± 0.173
|
0.290 ± 0.207
|
0.041 ± 0.015
|
0.361 ± 0.144
|
− 0.516 ± 0.248
|
|
0.0513
|
0.5726
|
0.3789
|
0.1651
|
0.0059
|
0.0138
|
0.0396
|
|
Glu/PC ae C32:2
|
− 1.121 ± 0.400
|
0.218 ± 0.091
|
− 0.113 ± 0.189
|
0.554 ± 0.226
|
0.039 ± 0.016
|
0.252 ± 0.157
|
− 0.817 ± 0.270
|
|
0.0061
|
0.0183
|
0.5520
|
0.0160
|
0.0160
|
0.1125
|
0.0031
|
|
Ile/PC ae C32:2
|
− 1.084 ± 0.329
|
0.241 ± 0.075
|
− 0.037 ± 0.156
|
0.473 ± 0.186
|
0.031 ± 0.013
|
0.170 ± 0.129
|
− 0.534 ± 0.222
|
|
0.0014
|
0.0017
|
0.8101
|
0.0124
|
0.0222
|
0.1933
|
0.0180
|
|
Val/PC ae C32:2
|
− 1.011 ± 0.300
|
0.189 ± 0.068
|
− 0.071 ± 0.142
|
0.499 ± 0.169
|
0.031 ± 0.012
|
0.183 ± 0.118
|
− 0.569 ± 0.202
|
|
0.0010
|
0.0064
|
0.6197
|
0.0039
|
0.0116
|
0.1241
|
0.0059
|
- Multiple linear regression analysis was used to perform the analysis after adjusting for age, sex and body mass index with total cholesterol, triglycerides, HDL-C, LDL-C, serum Hp level tertiles, carotid IMT and IAD as independent variables. β ± SE and P values are shown in table
- T2DM type 2 diabetes mellitus, Asn asparagine, Asp aspartate, Glu glutamic acid, Ile isoleucine, Val valine, Hp haptoglobin, HDL-C high-density lipoprotein-cholesterol, LDL-C low-density lipoprotein-cholesterol, IMT intima-media thickness, IAD inter-adventitial diameter
- P values < 0.05 are shown in italic
