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Table 1 Basic clinical characteristics of subjects in this study

From: Association between serum haptoglobin and carotid arterial functions: usefulness of a targeted metabolomics approach

Variable Low Hp Middle Hp High Hp P value
T2DM (n = 120)
 Number 39 40 41
 Age (years) 56.85 ± 11.18 56.88 ± 12.16 58.25 ± 11.46 0.8245
 Male/female 30/9 22/18 32/9 0.0410
 BMI (kg/m2) 24.69 ± 4.24 24.63 ± 3.25 24.62 ± 2.89 0.9959
 SBP (mmHg) 130 (120, 150) 127 (110, 134) 130 (120, 150) 0.0852
 DBP (mmHg) 80 (74, 90) 75 (70, 82) 80 (72, 90) 0.1756
 Duration of diabetes (years) 10 (4, 15) 10 (7, 10) 10 (4, 15) 0.8267
 HbA1c (%) 8.00 (7.20, 10.20) 8.40 (7.20, 10.30) 8.30 (7.20, 9.70) 0.9903
 Total cholesterol (mmol/L) 4.64 (4.28, 5.59) 4.61 (3.78, 5.37) 4.40 (3.87, 4.87) 0.3833
 Triglycerides (mmol/L) 1.50 (1.20, 2.20) 1.29 (0.79, 1.93) 1.39 (1.03, 1.65) 0.2756
 HDL-C (mmol/L) 1.09 (0.95, 1.20) 0.99 (0.88, 1.24) 1.00 (0.81, 1.10) 0.2181
 LDL-C (mmol/L) 2.76 ± 0.85 2.74 ± 0.76 2.65 ± 0.84 0.7488
 Carotid IMT (mm) 0.80 (0.70, 0.90) 0.75 (0.65, 0.90) 0.80 (0.70, 0.90) 0.3466
 Carotid IAD (mm) 6.17 ± 0.70 6.28 ± 0.78 6.65 ± 0.67 0.0088
 Serum Hp levels (mg/dL) 54.82 (3.60, 71.58) 103.20 (95.30, 107.27) 151.64 (131.12, 175.55) < 0.0001
Non-DM (n = 120)
 Number 39 40 41
 Age (years) 64.06 ± 4.31 64.10 ± 4.27 64.58 ± 4.15 0.8720
 Male/female 17/22 20/20 23/18 0.5378
 BMI (kg/m2) 24.11 ± 3.27 25.09 ± 3.18 25.64 ± 4.06 0.1522
 SBP (mmHg) 125 (120, 139) 129 (122, 138) 129 (123, 138) 0.5074
 DBP (mmHg) 81 (78, 87) 81 (78, 83) 82 (80, 87) 0.4709
 HbA1c (%) 5.64 ± 0.59 5.61 ± 0.65 5.82 ± 0.51 0.1398
 Total cholesterol (mmol/L) 4.36 (4.00, 4.89) 4.49 (3.98, 4.97) 4.40 (4.07, 4.79) 0.8007
 Triglycerides (mmol/L) 1.03 (0.80, 1.43) 1.10 (0.89, 1.41) 0.99 (0.80, 1.26) 0.7676
 HDL-C (mmol/L) 1.31 (1.09, 1.58) 1.29 (1.17, 1.52) 1.22 (1.14, 1.41) 0.6175
 LDL-C (mmol/L) 2.53 (2.25, 2.89) 2.56 (2.15, 2.97) 2.61 (2.28, 2.91) 0.7962
 Carotid IMT (mm) 0.64 ± 0.10 0.65 ± 0.09 0.66 ± 0.08 0.4667
 Serum Hp levels (mg/dL) 39.48 (17.23, 51.45) 99.41 (92.96, 113.38) 167.67 (140.35, 209.73) < 0.0001
  1. Data are shown as n or the mean ± standard deviation or median (interquartile range)
  2. T2DM type 2 diabetes mellitus, Non-DM non-diabetes mellitus, Hp haptoglobin, BMI body mass index, SBP systolic blood pressure, DBP diastolic blood pressure, HDL-C high-density lipoprotein-cholesterol, LDL-C low-density lipoprotein-cholesterol, IMT intima-media thickness, IAD inter-adventitial diameter
  3. P values < 0.05 are shown in italic