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Table 1 Basic clinical characteristics of subjects in this study

From: Association between serum haptoglobin and carotid arterial functions: usefulness of a targeted metabolomics approach

Variable

Low Hp

Middle Hp

High Hp

P value

T2DM (n = 120)

 Number

39

40

41

–

 Age (years)

56.85 ± 11.18

56.88 ± 12.16

58.25 ± 11.46

0.8245

 Male/female

30/9

22/18

32/9

0.0410

 BMI (kg/m2)

24.69 ± 4.24

24.63 ± 3.25

24.62 ± 2.89

0.9959

 SBP (mmHg)

130 (120, 150)

127 (110, 134)

130 (120, 150)

0.0852

 DBP (mmHg)

80 (74, 90)

75 (70, 82)

80 (72, 90)

0.1756

 Duration of diabetes (years)

10 (4, 15)

10 (7, 10)

10 (4, 15)

0.8267

 HbA1c (%)

8.00 (7.20, 10.20)

8.40 (7.20, 10.30)

8.30 (7.20, 9.70)

0.9903

 Total cholesterol (mmol/L)

4.64 (4.28, 5.59)

4.61 (3.78, 5.37)

4.40 (3.87, 4.87)

0.3833

 Triglycerides (mmol/L)

1.50 (1.20, 2.20)

1.29 (0.79, 1.93)

1.39 (1.03, 1.65)

0.2756

 HDL-C (mmol/L)

1.09 (0.95, 1.20)

0.99 (0.88, 1.24)

1.00 (0.81, 1.10)

0.2181

 LDL-C (mmol/L)

2.76 ± 0.85

2.74 ± 0.76

2.65 ± 0.84

0.7488

 Carotid IMT (mm)

0.80 (0.70, 0.90)

0.75 (0.65, 0.90)

0.80 (0.70, 0.90)

0.3466

 Carotid IAD (mm)

6.17 ± 0.70

6.28 ± 0.78

6.65 ± 0.67

0.0088

 Serum Hp levels (mg/dL)

54.82 (3.60, 71.58)

103.20 (95.30, 107.27)

151.64 (131.12, 175.55)

< 0.0001

Non-DM (n = 120)

 Number

39

40

41

–

 Age (years)

64.06 ± 4.31

64.10 ± 4.27

64.58 ± 4.15

0.8720

 Male/female

17/22

20/20

23/18

0.5378

 BMI (kg/m2)

24.11 ± 3.27

25.09 ± 3.18

25.64 ± 4.06

0.1522

 SBP (mmHg)

125 (120, 139)

129 (122, 138)

129 (123, 138)

0.5074

 DBP (mmHg)

81 (78, 87)

81 (78, 83)

82 (80, 87)

0.4709

 HbA1c (%)

5.64 ± 0.59

5.61 ± 0.65

5.82 ± 0.51

0.1398

 Total cholesterol (mmol/L)

4.36 (4.00, 4.89)

4.49 (3.98, 4.97)

4.40 (4.07, 4.79)

0.8007

 Triglycerides (mmol/L)

1.03 (0.80, 1.43)

1.10 (0.89, 1.41)

0.99 (0.80, 1.26)

0.7676

 HDL-C (mmol/L)

1.31 (1.09, 1.58)

1.29 (1.17, 1.52)

1.22 (1.14, 1.41)

0.6175

 LDL-C (mmol/L)

2.53 (2.25, 2.89)

2.56 (2.15, 2.97)

2.61 (2.28, 2.91)

0.7962

 Carotid IMT (mm)

0.64 ± 0.10

0.65 ± 0.09

0.66 ± 0.08

0.4667

 Serum Hp levels (mg/dL)

39.48 (17.23, 51.45)

99.41 (92.96, 113.38)

167.67 (140.35, 209.73)

< 0.0001

  1. Data are shown as n or the mean ± standard deviation or median (interquartile range)
  2. T2DM type 2 diabetes mellitus, Non-DM non-diabetes mellitus, Hp haptoglobin, BMI body mass index, SBP systolic blood pressure, DBP diastolic blood pressure, HDL-C high-density lipoprotein-cholesterol, LDL-C low-density lipoprotein-cholesterol, IMT intima-media thickness, IAD inter-adventitial diameter
  3. P values < 0.05 are shown in italic
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Cardiovascular Diabetology

ISSN: 1475-2840