Fig. 4

Metabolite ratios of two acidic amino acids to PC ae C32:2 in non-DM subjects. Non-DM non-diabetes mellitus, Hp haptoglobin, Asp aspartate, Glu glutamate. Dot plot a shows the association of blood metabolite ratio Asp to PC ae C32:2 (Log transformed) with serum Hp tertiles, P = 0.0012, β ± SE = 0.048 ± 0.015. Dot plot b shows the association of blood metabolite ratio Glu to PC ae C32:2 (Log transformed) with serum Hp tertiles, P = 0.0071, β ± SE = 0.043 ± 0.016. P values and beta values were determined by multiple linear regression adjusting for age, sex, body mass index, total cholesterol, triglycerides, high-density lipoprotein-cholesterol, low-density lipoprotein-cholesterol and carotid intima-media thickness. Metabolite ratios (Log transformed) are shown in dot plots; the median is indicated by the middle black solid line. The lower and upper quartiles are shown by the bottom and top black solid lines, respectively