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Table 3 Demographic and clinical data of diabetic subjects with and without PAD

From: Sortilin levels are associated with peripheral arterial disease in type 2 diabetic subjects

  WPAD PAD P value
(n = 80) (n = 74)
Male (%) 69 65 0.34
Age (years ± SD) 73.1 ± 6.4 69.8 ± 6.3 0.89
Body mass index (kg/m2) 24.3 ± 2.1 23.9 ± 2.8 0.52
Smoking (current) (%) 17 (21.25) 19 (25.67) 0.032
Hypertension (%) 35 (44.0) 47 (63.5) 0.024
Coronary artery disease (%) 25 (31.2) 39 (52.7) 0.031
Diabetes duration (years ± SD) 10.1 ± 6.1 11.6 ± 5.9 0.97
Total cholesterol (mmol/L) 5.97 (1.81) 5.87 (1.35) 0.78
HDL-cholesterol (mmol/L) 1.24 (1.21) 1.20 (1.21) 0.67
LDL-cholesterol (mmol/L) 2.82 (1.08) 2.78 (0.83) 0.73
Triglyceride (mmol/L) 2.32 (1.67) 1.98 (1.12) 0.99
Fasting glucose (mmol/L) 7.19 (1.12) 7.61 (1.85) 0.75
Glycated hemoglobin (%) 7.13 (1.41) 7.21 (1.84) 0.59
eGFR (mL/min per 1.73 m2) 72.12 (8.19) 67.98 (6.76 0.12
Aspartate aminotransferase (UI/L) 38.2 (4.5) 34.4 (3.8) 0.61
Alanine aminotransferase (UI/L) 41.1 (4.9) 44.3 (3.9) 0.45
Total bilirubin (mg/dL) 0.9 (0.3) 1.1 (0.4) 0.33
Alkaline phosphatase (UI/L) 109.6 (12.3) 112.3 (9.4) 0.56
Hemoglobin (g/dL) 11.6 (2.12) 12.1 (2.01) 0.98
White blood cells (× 10E3/μL) 5.9 (0.68) 6.1 (0.98) 0.85
Platelets (× 10E3/μL) 254 (15.2) 236 (17.3) 0.52
Treatment
 Diet only (%) 9 (11.25) 11 (14.86) 0.76
 Oral agents (%) 42 (52.5) 38 (51.35) 0.88
 Insulin therapy (%) 38 (47.5) 35 (47.29) 0.65
PAD
 1-Fontaine’s II (%)   36 (48.64)  
 2-Fontaine’s III (%)   24 (32.43)  
 2-Fontaine’s IV (%)   14 (18.91)  
  1. Data are number (%) and standard deviation (SD)