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Table 2 Criteria for PAD definition in patients without a history of lower limb amputation, PTA or by-pass surgery

From: Sortilin levels are associated with peripheral arterial disease in type 2 diabetic subjects

Clinical Criteria Instrumental criteria
Presence of claudication intermittens ABI < 0.90
Rest pain TcPO2 < 30 mmHg
Non-healing distal ulcer Ultrasonographic or radiologic finding of atherosclerotic narrowing, with a reduction of at least 50% of the lumen diameter, consistent with clinical symptoms
Gangrene Ultrasonographic finding of post-stenotic blood flow profile, consistent with symptoms