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Table 2 Criteria for PAD definition in patients without a history of lower limb amputation, PTA or by-pass surgery

From: Sortilin levels are associated with peripheral arterial disease in type 2 diabetic subjects

Clinical Criteria

Instrumental criteria

Presence of claudication intermittens

ABI < 0.90

Rest pain

TcPO2 < 30 mmHg

Non-healing distal ulcer

Ultrasonographic or radiologic finding of atherosclerotic narrowing, with a reduction of at least 50% of the lumen diameter, consistent with clinical symptoms

Gangrene

Ultrasonographic finding of post-stenotic blood flow profile, consistent with symptoms