Skip to main content

Advertisement

Table 2 The association between fifths of GIT scores and cause-specific mortality

From: Cognitive function in adolescence and the risk for premature diabetes and cardiovascular mortality in adulthood

Mortality cause Q1 Q2 Q3 Q4 Q5 Total
a. Cause-specific death according to GIT quintiles
All-cause, N (%) 8765 (1.97%) 6306 (1.31%) 6188 (1.41%) 5221 (1.11%) 4788 (1.09%) 31,268
 Incidence (event/105 person-years) 108.7 71.3 73.2 60.9 60.0 74.6
Total cardiovascular, N (%) 1075 (0.24%) 641 (0.13%) 624 (0.14%) 394 (0.08%) 334 (0.08%) 3068
 Incidence (event/105 person-years) 13.3 7.25 7.4 4.6 4.2 7.3
Coronary heart disease, N (%) 526 (0.12%) 288 (0.06%) 308 (0.07%) 165 (0.03%) 156 (0.04%) 1443
 Incidence (event/105 person-years) 6.5 3.3 3.6 1.9 1.9 3.4
Stroke, N (%) 172 (0.04%) 115 (0.02%) 110 (0.03%) 72 (0.02%) 45 (0.01%) 514
 Incidence (event/105 person-years) 2.1 1.3 1.3 0.8 0.6 1.2
Diabetes, N (%) 184 (0.04%) 98 (0.02%) 96 (0.02%) 51 (0.01%) 28 (0.01%) 457
 Incidence (event/105 person-years) 2.3 1.1 1.1 0.6 0.4 1.1
Non-CVD, non-diabetes, N (%) 7506 (1.68%) 5567 (1.16%) 5468 (1.24%) 4776 (1.01%) 4426 (1.01%) 27,743
 Incidence (event/105 person-years) 93.1 63.0 64.7 55.7 55.4 66.2
b. Cox proportional hazard models
All cause  (unadjusted) 1.84 (1.78, 1.91) 1.25 (1.20, 1.29) 1.21 (1.16, 1.25) 1.04 (1.00, 1.08) 1 4.10*10−231
All cause  (adjusted) 1.23 (1.17, 1.28) 1.08 (1.04, 1.13) 1.04 (1.00, 1.08) 1.01 (0.98, 1.06) 1 1.3*10−33
Total CVD  (unadjusted) 3.32 (2.93, 3.75) 1.92 (1.68, 2.19) 1.71 (1.49, 1.95) 1.15 (0.99, 1.33) 1 2.13*10−126
Total CVD  (adjusted) 1.76 (1.52, 2.04) 1.44 (1.24, 1.66) 1.27 (1.11, 1.46) 1.05 (0.91, 1.22) 1 1.3*10−14
CHD  (unadjusted) 3.49 (2.92, 4.18) 1.87 (1.54, 2.27) 1.8 (1.48, 2.18) 1.03 (0.83, 1.29) 1 1.21*10−66
CHD  (adjusted) 1.70 (1.37, 2.11) 1.36 (1.09, 1.68) 1.31 (1.07, 1.60) 0.95 (0.76, 1.18) 1 1.6*10−9
Stroke  (unadjusted) 3.96 (2.85, 5.50) 2.60 (1.84, 3.66) 2.22 (1.57, 3.15) 1.56 (1.08, 2.27) 1 5.06*10−24
Stroke  (adjusted) 2.03 (1.39, 2.98) 1.83 (1.26, 2.66) 1.61 (1.12, 2.30) 1.40 (0.96, 2.03) 1 3.3*10−6
Diabetes (unadjusted) 6.96 (4.68, 10.36) 3.76 (2.47, 5.72) 3.08 (2.02, 4.69) 1.81 (1.14, 2.87) 1 5.13*10−38
Diabetes  (adjusted) 3.14 (2.00, 4.94) 2.36 (1.5, 3.7) 2.04 (1.32, 3.15) 1.55 (0.97, 2.46) 1 3.2*10−9
Non CVD/diabetes  (unadjusted) 1.70 (1.64, 1.77) 1.18 (1.13, 1.23) 1.16 (1.11, 1.20) 1.02 (0.98, 1.06) 1 7.78*10−247
Non CVD/diabetes  (adjusted) 1.17 (1.12, 1.22) 1.04 (1.00, 1.09) 1.01 (0.97, 1.05) 1.01 (0.97, 1.05) 1 1.3*10−19
  1. The association between fifths of GIT scores (in comparison to highest quintile) and cause of death was determined using unadjusted and after adjustment for age, sex, birth year, body mass index (BMI), residential socioeconomic status, education and country of origin
  2. HR Hazard ratio, CI confidence interval, CHD coronary heart disease, CVD cardiovascular