|
PLACEBO
|
EMPA
|
MET
|
EMPA/MET
|
---|
Before
|
After
|
Before
|
After
|
Before
|
After
|
Before
|
After
|
---|
Average age (years)
|
43.1 ± 2.1
|
46.0 ± 2.3
|
46.4 ± 3.9
|
43.3 ± 2.6
|
Duration of diabetes (years)
|
22.2 ± 3.8
|
22.5 ± 3.7
|
23.2 ± 4.8
|
22.3 ± 3.2
|
HbA1c (%)
|
7.8 ± 0.2
|
7.7 ± 0.3
|
7.8 ± 0.1
|
7.4 ± 0.1
|
7.9 ± 0.2
|
7.7 ± 0.3
|
7.8 ± 0.2
|
7.2 ± 0.2*
|
Systolic BP (mmHg)
|
129.9 ± 4.0
|
127.4 ± 2.9
|
134.5 ± 3.0
|
127.2 ± 2.9
|
132.4 ± 3.1
|
125.9 ± 2.1
|
129.9 ± 2.6
|
124.8 ± 3.4
|
Diastolic BP (mmHg)
|
73.2 ± 5.4
|
77.0 ± 2.4
|
83.8 ± 2.6
|
81.9 ± 2.4
|
79.1 ± 1.5
|
79.8 ± 2.3
|
84.4 ± 1.1
|
73.7 ± 1.8
|
BMI (kg/m2)
|
28.3 ± 0.5
|
28.5 ± 0.31
|
28.9 ± 0.7
|
28.4 ± 0.6
|
28.0 ± 0.3
|
27.5 ± 0.3
|
28.9 ± 0.9
|
27.7 ± 1.0
|
Waist circumference (cm)
|
96.9 ± 3.9
|
95.2 ± 3.5
|
101.4 ± 2.9
|
97.1 ± 2.6
|
97.8 ± 4.0
|
97.9 ± 4.9
|
99.1 ± 3.9
|
97.7 ± 3.6
|
- Values are expressed as mean ± standard error of the means
- BP, blood pressure; BMI, body mass index; HbA1c, glycated haemoglobin
- * P < 0.05 for comparison within the group