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Table 2 Characteristics of ACS patients with diabetes/possible diabetes

From: Prevalence and in-hospital outcomes of diabetes among patients with acute coronary syndrome in China: findings from the Improving Care for Cardiovascular Disease in China-Acute Coronary Syndrome Project

 

All ACS

STEMI

NSTE-ACS

Diabetes/possible diabetes (N = 23,880)

No diabetes (N = 39,570)

p value

Diabetes/possible diabetes (N = 14,650)

No diabetes (N = 25,143)

p value

Diabetes/possible diabetes (N = 9230)

No diabetes (N = 14,427)

p value

Age, mean (SD), years

64.2 (11.9)

62.1 (12.7)

< 0.001

62.9 (12.0)

61.0 (12.9)

< 0.001

66.3 (11.3)

64.1 (12.2)

< 0.001

Women, n (%)

7159 (30.0)

8764 (22.2)

< 0.001

3904 (26.7)

4744 (18.9)

< 0.001

3255 (35.3)

4020 (27.9)

< 0.001

Vital signs

 SBP levels, mean (SD)

131.7 (24.3)

129.1 (22.9)

< 0.001

128.4 (24.2)

126.3 (22.9)

< 0.001

136.9 (23.5)

133.9 (22.1)

< 0.001

 DBP levels, mean (SD)

77.9 (14.5)

78.0 (14.3)

0.543

77.8 (15.0)

77.5 (14.6)

0.629

78.4 (13.5)

78.8 (13.6)

0.040

 Heart rate, mean (SD)

79.6 (17.2)

76.1 (15.5)

< 0.001

80.0 (17.5)

76.8 (15.8)

< 0.001

79.1 (16.6)

74.8 (14.8)

< 0.001

Risk factors

 Hypertension, n (%)

17,180 (71.9)

24,176 (61.1)

< 0.001

9961 (68.0)

14,350 (57.1)

< 0.001

7219 (78.2)

9826 (68.1)

< 0.001

 Elevated LDL-Ca, n (%)

18,024 (83.7)

30,517 (85.1)

0.010

11,375 (86.5)

19,760 (86.9)

0.257

6649 (79.3)

10,757 (82.0)

< 0.001

 Low HDL-Cb, n (%)

10,634 (49.1)

15,238 (42.4)

< 0.001

6293 (47.6)

9768 (42.8)

< 0.001

4341 (51.5)

5470 (41.6)

< 0.001

 Elevated TGc, n (%)

5194 (23.9)

5911 (16.4)

< 0.001

3094 (23.3)

3659 (16.0)

< 0.001

2100 (24.9)

2252 (17.1)

< 0.001

 Current smoker, n (%)

  Men

8499 (50.8)

17,421 (56.6)

< 0.001

5848 (54.4)

12,081 (59.2)

< 0.001

2651 (44.4)

5340 (51.3)

< 0.001

  Women

572 (8.0)

851 (9.7)

< 0.001

371 (9.5)

547 (11.5)

0.002

201 (6.2)

304 (7.6)

0.021

History of diseases

 CHD, n (%)

3197 (13.4)

3766 (9.5)

< 0.001

1186 (8.1)

1491 (5.9)

< 0.001

2011 (21.8)

2275 (15.8)

< 0.001

 Cerebrovascular disease, n (%)

2911 (12.2)

3200 (8.1)

< 0.001

1587 (10.8)

1850 (7.4)

< 0.001

1324 (14.3)

1350 (9.4)

< 0.001

 Heart failure, n (%)

706 (3.0)

553 (1.4)

< 0.001

199 (1.4)

178 (0.7)

< 0.001

507 (5.5)

375 (2.6)

< 0.001

 Atrial fibrillation, n (%)

674 (2.8)

855 (2.2)

< 0.001

253 (1.7)

328 (1.3)

0.001

421 (4.6)

527 (3.7)

0.001

 PAD, n (%)

293 (1.2)

325 (0.8)

< 0.001

102 (0.7)

145 (0.6)

0.143

191 (2.1)

180 (1.3)

<0.001

 Renal failure, n (%)

645 (2.7)

423 (1.1)

< 0.001

237 (1.6)

188 (0.8)

< 0.001

408 (4.4)

235 (1.6)

< 0.001

Severe clinical conditions

 Heart failured, n (%)

2805 (11.9)

2813 (7.2)

< 0.001

1683 (11.6)

1816 (7.3)

< 0.001

1122 (12.3)

997 (7.0)

< 0.001

 Cardiac shocke, n (%)

874 (3.7)

1049 (2.7)

< 0.001

728 (5.0)

892 (3.6)

< 0.001

146 (1.6)

157 (1.1)

0.001

 Cardiac arrestf, n (%)

522 (2.2)

693 (1.8)

< 0.001

427 (2.9)

605 (2.4)

0.005

95 (1.0)

88 (0.6)

< 0.001

 Killip classg, n (%)

  

< 0.001

  

< 0.001

  

< 0.001

  II–III

6700 (28.1)

9406 (23.8)

 

3924 (26.9)

5870 (23.4)

 

2776 (30.2)

3536 (24.6)

 

  IV

1569 (6.6)

1725 (4.4)

 

1147 (7.9)

1325 (5.3)

 

422 (4.6)

400 (2.8)

 

 Fivefold elevated myocardial injury markerh

16,800 (72.7)

26,759 (70.5)

< 0.001

11,779 (82.6)

19,638 (81.0)

< 0.001

5021 (56.8)

7121 (51.9)

< 0.001

 GRACE score ≥ 140i, n (%)

8632 (39.2)

11,196 (31.2)

< 0.001

9074 (65.7)

16,819 (72)

< 0.001

3887 (47.3)

4644 (37.0)

< 0.001

Type of ACS, n (%)

  

< 0.001

      

 STEMI

14,650 (61.4)

25,143 (63.5)

 

–

–

–

–

–

–

 NSTE-ACS

9230 (38.7)

14,427 (36.5)

 

–

–

–

–

–

–

Patients with referral, n (%)

10,148 (42.5)

18,396 (46.5)

< 0.001

7198 (49.2)

13,347 (53.1)

< 0.001

2950 (32.0)

5049 (35.0)

< 0.001

  1. ACS acute coronary syndrome, LDL-C low-density lipoprotein cholesterol, HDL-C high-density lipoprotein cholesterol, TG triglyceride, CHD coronary heart disease, PAD peripheral artery disease, GRACE Global Registry of Acute Coronary Events, ACS acute coronary syndrome, STEMI ST-segment elevation myocardial infarction, NSTE-ACS non-ST-segment elevation acute coronary syndrome
  2. a Elevated LDL-C, data of LDL-C were not available for 6060 patients
  3. b Decreased HDL-C, data of HDL-C were not available for 5860 patients
  4. c Elevated TG, data of TG were not available for 5614 patients
  5. d Heart failure, data of heart failure were not available for 766 patients
  6. e Cardiac shock, data of cardiac shock were not available for 743 patients
  7. f Cardiac arrest, data of cardiac arrest were not available for 807 patients
  8. g Killip class, data of first Killip class were not available for 181 patients
  9. h Fivefold elevated myocardial injury markers, data of myocardial injury markers were not available for 2390 patients
  10. i GRACE score, data of cardiac arrest were not available for 5504 patients
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Cardiovascular Diabetology

ISSN: 1475-2840