Age, mean (SD), years
|
64.2 (11.9)
|
62.1 (12.7)
|
< 0.001
|
62.9 (12.0)
|
61.0 (12.9)
|
< 0.001
|
66.3 (11.3)
|
64.1 (12.2)
|
< 0.001
|
Women, n (%)
|
7159 (30.0)
|
8764 (22.2)
|
< 0.001
|
3904 (26.7)
|
4744 (18.9)
|
< 0.001
|
3255 (35.3)
|
4020 (27.9)
|
< 0.001
|
Vital signs
|
SBP levels, mean (SD)
|
131.7 (24.3)
|
129.1 (22.9)
|
< 0.001
|
128.4 (24.2)
|
126.3 (22.9)
|
< 0.001
|
136.9 (23.5)
|
133.9 (22.1)
|
< 0.001
|
DBP levels, mean (SD)
|
77.9 (14.5)
|
78.0 (14.3)
|
0.543
|
77.8 (15.0)
|
77.5 (14.6)
|
0.629
|
78.4 (13.5)
|
78.8 (13.6)
|
0.040
|
Heart rate, mean (SD)
|
79.6 (17.2)
|
76.1 (15.5)
|
< 0.001
|
80.0 (17.5)
|
76.8 (15.8)
|
< 0.001
|
79.1 (16.6)
|
74.8 (14.8)
|
< 0.001
|
Risk factors
|
Hypertension, n (%)
|
17,180 (71.9)
|
24,176 (61.1)
|
< 0.001
|
9961 (68.0)
|
14,350 (57.1)
|
< 0.001
|
7219 (78.2)
|
9826 (68.1)
|
< 0.001
|
Elevated LDL-Ca, n (%)
|
18,024 (83.7)
|
30,517 (85.1)
|
0.010
|
11,375 (86.5)
|
19,760 (86.9)
|
0.257
|
6649 (79.3)
|
10,757 (82.0)
|
< 0.001
|
Low HDL-Cb, n (%)
|
10,634 (49.1)
|
15,238 (42.4)
|
< 0.001
|
6293 (47.6)
|
9768 (42.8)
|
< 0.001
|
4341 (51.5)
|
5470 (41.6)
|
< 0.001
|
Elevated TGc, n (%)
|
5194 (23.9)
|
5911 (16.4)
|
< 0.001
|
3094 (23.3)
|
3659 (16.0)
|
< 0.001
|
2100 (24.9)
|
2252 (17.1)
|
< 0.001
|
Current smoker, n (%)
|
Men
|
8499 (50.8)
|
17,421 (56.6)
|
< 0.001
|
5848 (54.4)
|
12,081 (59.2)
|
< 0.001
|
2651 (44.4)
|
5340 (51.3)
|
< 0.001
|
Women
|
572 (8.0)
|
851 (9.7)
|
< 0.001
|
371 (9.5)
|
547 (11.5)
|
0.002
|
201 (6.2)
|
304 (7.6)
|
0.021
|
History of diseases
|
CHD, n (%)
|
3197 (13.4)
|
3766 (9.5)
|
< 0.001
|
1186 (8.1)
|
1491 (5.9)
|
< 0.001
|
2011 (21.8)
|
2275 (15.8)
|
< 0.001
|
Cerebrovascular disease, n (%)
|
2911 (12.2)
|
3200 (8.1)
|
< 0.001
|
1587 (10.8)
|
1850 (7.4)
|
< 0.001
|
1324 (14.3)
|
1350 (9.4)
|
< 0.001
|
Heart failure, n (%)
|
706 (3.0)
|
553 (1.4)
|
< 0.001
|
199 (1.4)
|
178 (0.7)
|
< 0.001
|
507 (5.5)
|
375 (2.6)
|
< 0.001
|
Atrial fibrillation, n (%)
|
674 (2.8)
|
855 (2.2)
|
< 0.001
|
253 (1.7)
|
328 (1.3)
|
0.001
|
421 (4.6)
|
527 (3.7)
|
0.001
|
PAD, n (%)
|
293 (1.2)
|
325 (0.8)
|
< 0.001
|
102 (0.7)
|
145 (0.6)
|
0.143
|
191 (2.1)
|
180 (1.3)
|
<0.001
|
Renal failure, n (%)
|
645 (2.7)
|
423 (1.1)
|
< 0.001
|
237 (1.6)
|
188 (0.8)
|
< 0.001
|
408 (4.4)
|
235 (1.6)
|
< 0.001
|
Severe clinical conditions
|
Heart failured, n (%)
|
2805 (11.9)
|
2813 (7.2)
|
< 0.001
|
1683 (11.6)
|
1816 (7.3)
|
< 0.001
|
1122 (12.3)
|
997 (7.0)
|
< 0.001
|
Cardiac shocke, n (%)
|
874 (3.7)
|
1049 (2.7)
|
< 0.001
|
728 (5.0)
|
892 (3.6)
|
< 0.001
|
146 (1.6)
|
157 (1.1)
|
0.001
|
Cardiac arrestf, n (%)
|
522 (2.2)
|
693 (1.8)
|
< 0.001
|
427 (2.9)
|
605 (2.4)
|
0.005
|
95 (1.0)
|
88 (0.6)
|
< 0.001
|
Killip classg, n (%)
| | |
< 0.001
| | |
< 0.001
| | |
< 0.001
|
II–III
|
6700 (28.1)
|
9406 (23.8)
| |
3924 (26.9)
|
5870 (23.4)
| |
2776 (30.2)
|
3536 (24.6)
| |
IV
|
1569 (6.6)
|
1725 (4.4)
| |
1147 (7.9)
|
1325 (5.3)
| |
422 (4.6)
|
400 (2.8)
| |
Fivefold elevated myocardial injury markerh
|
16,800 (72.7)
|
26,759 (70.5)
|
< 0.001
|
11,779 (82.6)
|
19,638 (81.0)
|
< 0.001
|
5021 (56.8)
|
7121 (51.9)
|
< 0.001
|
GRACE score ≥ 140i, n (%)
|
8632 (39.2)
|
11,196 (31.2)
|
< 0.001
|
9074 (65.7)
|
16,819 (72)
|
< 0.001
|
3887 (47.3)
|
4644 (37.0)
|
< 0.001
|
Type of ACS, n (%)
| | |
< 0.001
| | | | | | |
STEMI
|
14,650 (61.4)
|
25,143 (63.5)
| |
–
|
–
|
–
|
–
|
–
|
–
|
NSTE-ACS
|
9230 (38.7)
|
14,427 (36.5)
| |
–
|
–
|
–
|
–
|
–
|
–
|
Patients with referral, n (%)
|
10,148 (42.5)
|
18,396 (46.5)
|
< 0.001
|
7198 (49.2)
|
13,347 (53.1)
|
< 0.001
|
2950 (32.0)
|
5049 (35.0)
|
< 0.001
|