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Fig. 4 | Cardiovascular Diabetology

Fig. 4

From: A SGLT2 inhibitor dapagliflozin suppresses prolonged ventricular-repolarization through augmentation of mitochondrial function in insulin-resistant metabolic syndrome rats

Fig. 4

Effects of DAPA or INSU treatment on the voltage-dependent repolarizing K+-channel currents in freshly isolated cardiomyocytes. a Demonstration of representative original repolarizing K+-channel traces for all groups. The current–voltage relations (I–V characteristics) of K+ channels (b) and maximum outward (c, + 70 mV) and inward currents (d, − 120 mV) in DAPA or INSU treated MetS rats compared to MetS rats and age-matched control rats. The total number of cells/group/protocol; n = 12–15. Significance level at *p < 0.05 vs. CON group and #p < 0.05 vs. MetS group

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