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Fig. 2 | Cardiovascular Diabetology

Fig. 2

From: A SGLT2 inhibitor dapagliflozin suppresses prolonged ventricular-repolarization through augmentation of mitochondrial function in insulin-resistant metabolic syndrome rats

Fig. 2

Assessment of in vivo electrical activity of the hearts from DAPA or INSU administrated Mets rats. a Representative in situ ECG traces and b calculated ECG parameters including the R–R and Q–T intervals from DAPA or INSU treated MetS group compared to either MetS or age-matched control rats. c Heart rate was estimated from ECG traces. The representative pressure changes (inset) of the LVDP changes (d) and the rates of pressure development and decay (± dP/dt) of LVDP (e). Data presenting as mean (± SEM) values. The total number of rats/group/protocol; n = 6–7. Significance level at *p < 0.05 vs. CON group and #p < 0.05 vs. MetS group

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