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Table 3 Coagulation and fibrin clot properties in T2D patients

From: Polyhedrocytes in blood clots of type 2 diabetic patients with high cardiovascular risk: association with glycemia, oxidative stress and platelet activation

Variable

All subjects (n = 97)

Low polyhedrocytes group (n = 14)

High polyhedrocytes group (n = 83)

p-value

Lag time, min

2.90 (2.56–3.67)

2.95 (2.54–3.59)

2.81 (2.57–3.67)

0.93

ETP, nM × min

1367.6 (1289.9–1504.8)

1338.7 (1128.0–1380.5)

1382.5 (1291.6–1511.4)

0.15

Peak thrombin generation, nM

264.3 (222.9–309.3)

240.3 (224.4–268.2)

266.0 (222.2–310.9)

0.27

ttPeak, min

5.81 (5.00–7.00)

5.94 (5.48–6.90)

5.67 (5.00–7.05)

0.45

Ks, × 10−9 cm2

5.72 (4.30–6.84)

6.77 (5.56–7.69)

5.56 (4.25–6.57)

0.011

CLT, min

112.0 (100.0–127.0)

108.0 (96.0–114.3)

115.0 (103.0–130.0)

0.037

  1. Values are given as mean ± SD or median (interquartile range)
  2. Low polyhedrocytes group represents lowest 10% of the observations. High polyhedrocytes group represents highest 90% of the observations
  3. ETP endogenous thrombin potential, ttPeak time to thrombin generation peak, Ks, fibrin clot permeability coefficient, CLT clot lysis time