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Table 3 Coagulation and fibrin clot properties in T2D patients

From: Polyhedrocytes in blood clots of type 2 diabetic patients with high cardiovascular risk: association with glycemia, oxidative stress and platelet activation

Variable All subjects (n = 97) Low polyhedrocytes group (n = 14) High polyhedrocytes group (n = 83) p-value
Lag time, min 2.90 (2.56–3.67) 2.95 (2.54–3.59) 2.81 (2.57–3.67) 0.93
ETP, nM × min 1367.6 (1289.9–1504.8) 1338.7 (1128.0–1380.5) 1382.5 (1291.6–1511.4) 0.15
Peak thrombin generation, nM 264.3 (222.9–309.3) 240.3 (224.4–268.2) 266.0 (222.2–310.9) 0.27
ttPeak, min 5.81 (5.00–7.00) 5.94 (5.48–6.90) 5.67 (5.00–7.05) 0.45
Ks, × 10−9 cm2 5.72 (4.30–6.84) 6.77 (5.56–7.69) 5.56 (4.25–6.57) 0.011
CLT, min 112.0 (100.0–127.0) 108.0 (96.0–114.3) 115.0 (103.0–130.0) 0.037
  1. Values are given as mean ± SD or median (interquartile range)
  2. Low polyhedrocytes group represents lowest 10% of the observations. High polyhedrocytes group represents highest 90% of the observations
  3. ETP endogenous thrombin potential, ttPeak time to thrombin generation peak, Ks, fibrin clot permeability coefficient, CLT clot lysis time