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Table 2 Laboratory investigations

From: Polyhedrocytes in blood clots of type 2 diabetic patients with high cardiovascular risk: association with glycemia, oxidative stress and platelet activation

Variable All subjects (n = 97) Low polyhedrocytes group (n = 14) High polyhedrocytes group (n = 83) p-value
Fibrinogen, g/L 3.31 ± 0.58 2.90 ± 0.46 3.38 ± 0.57 0.004
INR 1.00 (0.96–1.03) 1.02 (0.98–1.06) 0.99 (0.95–1.03) 0.22
aPTT, sec 25.00 (23.95–26.20) 24.75 (24.30–25.10) 25.10 (23.60–26.30) 0.80
WBC, 103/µL 6.93 ± 1.61 7.51 ± 1.62 6.83 ± 1.59 0.15
RBC,106/µL 4.64 (4.31–4.94) 4.62 (4.21–5.29) 4.64 (4.31–4.92) 0.82
HGB, g/dL 13.60 (12.90–14.50) 13.15 (11.98–14.33) 13.60 (13.00–14.50) 0.08
HCT, % 40.20 (38.70–42.90) 39.25 (36.30–42.43) 40.30 (38.70–42.90) 0.30
RDW, % 13.50 (13.00–14.50) 14.80 (13.00–15.90) 13.50 (12.90–14.40) 0.034
PLT 103/µL 204.00 (161.50–249.50) 207.50 (157.50–252.50) 204.00 (166.00–250.00) 0.87
PDW, fL 12.60 (11.40–14.50) 13.20 (11.40–14.80) 12.35 (11.38–14.50) 0.56
Glucose, mmol/L 6.60 (5.90–7.75) 5.70 (5.45–6.83) 6.60 (6.10–7.80) 0.018
HbA1c, % 6.40 (5.93–7.10) 6.50 (5.60–7.08) 6.40 (6.00–7.13) 0.78
Creatinine, µmol/L 82.00 (69.50–96.50) 81.00 (72.25–104.75) 82.00 (68.00–96.00) 0.72
eGFR (mL/min/1.73 m2) 76.97 ± 19.10 79.14 ± 22.79 76.60 ± 18.55 0.64
TC, mmol/L 3.93 (3.25–4.74) 3.69 (3.17–4.16) 4.08 (3.26–4.75) 0.30
LDL-C, mmol/L 2.19 (1.67–3.02) 1.79 (1.61–2.80) 2.26 (1.78–3.04) 0.31
HDL-C, mmol/L 1.22 (0.95–1.49) 1.24 (0.83–1.41) 1.22 (0.98–1.53) 0.78
TG, mmol/L 1.33 (1.03–1.73) 1.27 (0.98–2.09) 1.37 (1.03–1.73) 0.67
TSH, mIU/L 1.39 (0.84–2.05) 0.98 (0.88–1.88) 1.48 (0.84–2.12) 0.57
hsCRP, mg/L 2.29 (0.95–4.00) 1.35 (0.97–2.43) 3.02 (0.95–4.23) 0.11
  1. Values are given as mean ± SD or median (interquartile range)
  2. Low polyhedrocytes group represents lowest 10% of the observations. High polyhedrocytes group represents highest 90% of the observations
  3. aPTT activated partial thromboplastin time, eGFR estimated glomerular filtration rate based on a Modification of Diet in Renal Disease (MDRD) formula, HDL-C high-density lipoprotein cholesterol; HGB, hemoglobin, HCT hematocrit, hsCRP high sensitivity C-reactive protein, INR international normalized ratio, LDL-C low-density lipoprotein cholesterol, PDW platelet distribution width, RBC red blood cells, RDW red blood cell distribution width, PLT platelet count, TC total cholesterol, TG triglycerides, TSH thyroid-stimulating hormone, WBC white blood cells, ACEI angiotensin-converting-enzyme inhibitors, ARB angiotensin receptor blockers, BMI body mass index, MI myocardial infarction, T2D type 2 diabetes