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Table 2 Distribution and in-hospital mortality according to the study variables of type 2 diabetes (T2DM) patients and matched nondiabetic controls with a mechanical surgical aortic valve replacement (SAVR)

From: Impact of type 2 diabetes mellitus in the utilization and in-hospital outcomes of surgical aortic valve replacement in Spain (2001–2015)

  T2DM Matched non-T2DM P IHM T2DM IHM matched non-T2DM p
Year, n (%)
 2001–2003 1380 (15.7) 1380 (15.7) NA 140 (10.1) 116 (8.4) 0.116
 2004–2006 1696 (19.2) 1696 (19.2) 134 (7.9) 148 (8.7) 0.382
 2007–2009 1747 (19.8) 1747 (19.8) 143 (8.2) 152 (8.7) 0.585
 2010–2012 1954 (22.2) 1954 (22.2) 115 (5.9) 143 (7.3) 0.073
 2013–2015 2037 (23.1) 2037 (23.1) 95 (4.7) 126 (6.2) 0.031
Sex, n (%)
 Male 5260 (59.7) 5260 (59.7) NA 317 (6.0) 387 (7.4) 0.006
 Female 3554 (40.3) 3554 (40.3) 310 (8.7) 298 (8.4) 0.611
Age in years, mean (SD) 68.65 (8.2) 68.65 (8.2) NA 71.3 (7.6) 71.56 (7.6) 0.732
Age group, mean (SD), years
 40–64 2624 (29.8) 2624 (29.8) NA 114 (4.3) 119 (4.5) 0.740
 65–74 3837 (43.5) 3837 (43.5) 277 (7.2) 287 (7.5) 0.662
 75–84 2275 (25.8) 2275 (25.8) 227 (9.9) 272 (11.9) 0.033
 ≥ 85 78 (0.9) 78 (0.9) 9 (11.5) 7 (8.9) 0.566
CCI, mean (SD) 0.7 (0.7) 0.7 (0.6) 0.033 1.2 (0.9) 1.13 (0.9) 0.742
CCI, n (%)
 0 4286 (48.6) 4306 (48.8) 0.061 159 (3.7) 199 (4.6) 0.133
 1 2982 (33.8) 3127 (35.5) 261 (8.7) 265 (8.5) 0.810
 2+ 1546 (17.5) 1381 (15.7) 207 (13.4) 221 (16) 0.593
COPD, n (%)
 No 7903 (89.7) 8049 (91.3) < 0.001 559 (7.1) 621 (7.7) 0.073
 Yes 911 (10.3) 765 (8.7) 68 (7.5) 64 (8.4) 0.495
Renal dysfunction, n (%)
 No 8075 (91.6) 8287 (94.0) < 0.001 533 (6.6) 618 (7.5) 0.046
 Yes 739 (8.4) 527 (6.0) 94 (12.7) 67 (12.7) 0.410
Coronary artery disease, n (%)
 No 5133 (58.2) 6255 (71.0) < 0.001 301 (5.9) 401 (6.4) 0.226
 Yes 3681 (41.8) 2559 (29.0) 326 (8.9) 284 (11.1) 0.201
Occlusive peripheral arterial disease, n (%)
 No 7815 (88.7) 7236 (82.1) < 0.001 553 (7.1) 561 (7.7) 0.216
 Yes 999 (11.3) 1578 (17.9) 74 (7.4) 124 (7.9) 0.866
Atrial fibrillation, n (%)
 No 6224 (70.6) 6034 (68.5) 0.002 432 (6.9) 489 (8.1) 0.080
 Yes 2590 (29.4) 2780 (31.5) 195 (7.5) 196 (7.0) 0.222
CABG, n (%)
 No 6341 (71.9) 7128 (80.9) < 0.001 420 (6.6) 480 (6.7) 0.636
 Yes 2473 (28.1) 1686 (19.1) 207 (8.4) 205 (12.2) 0.118
Pacemaker implantation, n (%)
 No 8466 (96.0) 8446 (95.8) 0.442 609 (7.2) 656 (7.8) 0.106
 Yes 348 (3.9) 368 (4.2) 18 (5.2) 29 (7.9) 0.146
LOHS, mean (SD) 20.1 (17.7) 19.1 (17.2) < 0.001 24.7 (23.6) 25.01 (24.4) 0.617
  1. The p value for the difference between patients with type 2 diabetes and matched controls was calculated with the bivariate conditional logistic regression model
  2. CABG, Coronary artery bypass surgery; CCI, Charlson Comorbidity Index; COPD, chronic obstructive pulmonary disease; LOHS, length of hospital stay; IHM, in-hospital mortality; NA, not applicable, as this is a matching variable