Table 2 Distribution and in-hospital mortality according to the study variables of type 2 diabetes (T2DM) patients and matched nondiabetic controls with a mechanical surgical aortic valve replacement (SAVR)
T2DM | Matched non-T2DM | P | IHM T2DM | IHM matched non-T2DM | p | |
|---|---|---|---|---|---|---|
Year, n (%) | ||||||
2001–2003 | 1380 (15.7) | 1380 (15.7) | NA | 140 (10.1) | 116 (8.4) | 0.116 |
2004–2006 | 1696 (19.2) | 1696 (19.2) | 134 (7.9) | 148 (8.7) | 0.382 | |
2007–2009 | 1747 (19.8) | 1747 (19.8) | 143 (8.2) | 152 (8.7) | 0.585 | |
2010–2012 | 1954 (22.2) | 1954 (22.2) | 115 (5.9) | 143 (7.3) | 0.073 | |
2013–2015 | 2037 (23.1) | 2037 (23.1) | 95 (4.7) | 126 (6.2) | 0.031 | |
Sex, n (%) | ||||||
Male | 5260 (59.7) | 5260 (59.7) | NA | 317 (6.0) | 387 (7.4) | 0.006 |
Female | 3554 (40.3) | 3554 (40.3) | 310 (8.7) | 298 (8.4) | 0.611 | |
Age in years, mean (SD) | 68.65 (8.2) | 68.65 (8.2) | NA | 71.3 (7.6) | 71.56 (7.6) | 0.732 |
Age group, mean (SD), years | ||||||
40–64 | 2624 (29.8) | 2624 (29.8) | NA | 114 (4.3) | 119 (4.5) | 0.740 |
65–74 | 3837 (43.5) | 3837 (43.5) | 277 (7.2) | 287 (7.5) | 0.662 | |
75–84 | 2275 (25.8) | 2275 (25.8) | 227 (9.9) | 272 (11.9) | 0.033 | |
≥ 85 | 78 (0.9) | 78 (0.9) | 9 (11.5) | 7 (8.9) | 0.566 | |
CCI, mean (SD) | 0.7 (0.7) | 0.7 (0.6) | 0.033 | 1.2 (0.9) | 1.13 (0.9) | 0.742 |
CCI, n (%) | ||||||
0 | 4286 (48.6) | 4306 (48.8) | 0.061 | 159 (3.7) | 199 (4.6) | 0.133 |
1 | 2982 (33.8) | 3127 (35.5) | 261 (8.7) | 265 (8.5) | 0.810 | |
2+ | 1546 (17.5) | 1381 (15.7) | 207 (13.4) | 221 (16) | 0.593 | |
COPD, n (%) | ||||||
No | 7903 (89.7) | 8049 (91.3) | < 0.001 | 559 (7.1) | 621 (7.7) | 0.073 |
Yes | 911 (10.3) | 765 (8.7) | 68 (7.5) | 64 (8.4) | 0.495 | |
Renal dysfunction, n (%) | ||||||
No | 8075 (91.6) | 8287 (94.0) | < 0.001 | 533 (6.6) | 618 (7.5) | 0.046 |
Yes | 739 (8.4) | 527 (6.0) | 94 (12.7) | 67 (12.7) | 0.410 | |
Coronary artery disease, n (%) | ||||||
No | 5133 (58.2) | 6255 (71.0) | < 0.001 | 301 (5.9) | 401 (6.4) | 0.226 |
Yes | 3681 (41.8) | 2559 (29.0) | 326 (8.9) | 284 (11.1) | 0.201 | |
Occlusive peripheral arterial disease, n (%) | ||||||
No | 7815 (88.7) | 7236 (82.1) | < 0.001 | 553 (7.1) | 561 (7.7) | 0.216 |
Yes | 999 (11.3) | 1578 (17.9) | 74 (7.4) | 124 (7.9) | 0.866 | |
Atrial fibrillation, n (%) | ||||||
No | 6224 (70.6) | 6034 (68.5) | 0.002 | 432 (6.9) | 489 (8.1) | 0.080 |
Yes | 2590 (29.4) | 2780 (31.5) | 195 (7.5) | 196 (7.0) | 0.222 | |
CABG, n (%) | ||||||
No | 6341 (71.9) | 7128 (80.9) | < 0.001 | 420 (6.6) | 480 (6.7) | 0.636 |
Yes | 2473 (28.1) | 1686 (19.1) | 207 (8.4) | 205 (12.2) | 0.118 | |
Pacemaker implantation, n (%) | ||||||
No | 8466 (96.0) | 8446 (95.8) | 0.442 | 609 (7.2) | 656 (7.8) | 0.106 |
Yes | 348 (3.9) | 368 (4.2) | 18 (5.2) | 29 (7.9) | 0.146 | |
LOHS, mean (SD) | 20.1 (17.7) | 19.1 (17.2) | < 0.001 | 24.7 (23.6) | 25.01 (24.4) | 0.617 |