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Table 1 Clinical characteristics and in-hospital outcomes of hospitalized patients who underwent surgical aortic valve replacement (SAVR) in Spain from 2001 to 2015 according to T2DM status

From: Impact of type 2 diabetes mellitus in the utilization and in-hospital outcomes of surgical aortic valve replacement in Spain (2001–2015)

 

T2DM

2001–2003

2004–2006

2007–2009

2010–2012

2013–2015

Total

Trend

Number of SAVR

Yes

1979

3001

3582

4637

5179

18,378

NA

No

9897

11,329

11,832

12,955

13,832

59,845

NA

Prevalence of T2DM

Yes

16.7

20.9

23.2

26.4

27.2

23.5

< 0.001

Age, mean (SD)abcdef

Yes

70.2 (7.5)

70.9 (7.4)

71.6 (7.6)

72.5 (7.7)

72.8 (7.8)

71.9 (7.7)

< 0.001

No

67.8 (9.5)

69.1 (9.6)

69.7 (9.8)

70.7 (10.1)

71.0 (10.0)

69.8 (9.9)

< 0.001

Female sex, n (%)abcdf

Yes

943 (47.6)

1312 (43.7)

1525 (42.6)

1934 (41.7)

2035 (39.3)

7749 (42.2)

< 0.001

No

3795 (38.3)

4382 (38.7)

4582 (38.7)

5172 (39.9)

5398 (39.0)

23,329 (38.9)

0.079

CCI, mean (SD)acef

Yes

0.65 (0.5)

0.70 (0.6)

0.73 (0.7)

0.74 (0.6)

0.80 (0.7)

0.74 (0.7)

< 0.001

No

0.59 (0.5)

0.67 (0.5)

0.69 (0.5)

0.73 (0.6)

0.76 (0.7)

0.70 (0.6)

< 0.001

Mechanical SAVR, n (%)abcdef

Yes

1384 (69.9)

1702 (56.7)

1747 (48.8)

1957 (42.2)

2045 (39.5)

8835 (48.1)

< 0.001

No

7146 (72.2)

6909 (61.0)

6137 (51.9)

5952 (45.9)

5900 (42.6)

32,044 (53.5)

< 0.001

Bioprosthetic SAVR, n (%)abcdef

Yes

595 (30.1)

1299 (43.3)

1835 (51.2)

2680 (57.8)

3134 (60.5)

9543 (51.9)

< 0.001

No

2751 (27.8)

4420 (39.0)

5695 (48.1)

7003 (54.1)

7932 (57.3)

27,801 (46.5)

< 0.001

CABG, n (%)abcdef

Yes

566 (28.6)

983 (32.8)

1133 (31.6)

1320 (28.5)

1432 (27.6)

5434 (29.6)

< 0.001

No

1838 (18.6)

2348 (20.7)

2586 (21.9)

2745 (21.2)

2893 (20.9)

12,410 (20.8)

< 0.001

Pacemaker implantation, n (%)

Yes

77 (3.9)

121 (4.0)

189 (5.3)

193 (4.2)

234 (4.5)

814 (4.4)

0.419

No

337 (3.4)

439 (3.9)

623 (5.3)

520 (4.0)

568 (4.1)

2487 (4.1)

0.030

LOHS, mean (SD)abcef

Yes

22.77 (16.6)

22.00 (21.1)

21.16 (18.0)

17.60 (13.7)

15.86 (12.9)

19.08 (16.4)

< 0.001

No

20.41 (16.3)

19.89 (16.5)

19.48 (16.9)

17.64 (17.1)

16.36 (15.8)

18.59 (16.6)

< 0.001

IHM, n (%)def

Yes

176 (8.9)

230 (7.7)

254 (7.1)

226 (4.9)

201 (3.9)

1087 (5.9)

< 0.001

No

773 (7.8)

895 (7.9)

833 (7.0)

799 (6.2)

701 (5.1)

4001 (6.7)

< 0.001

  1. CABG, coronary artery bypass surgery; CCI, Charlson Comorbidity Index; LOHS, Length of hospital stay; IHM, in-hospital mortality, NA, not applicable
  2. ap < 0.05 for difference when comparing patients with and without T2DM (2001–2003). b p < 0.05 for difference when comparing patients with and without T2DM (2004–2006). c p < 0.05 for difference when comparing patients with and without T2DM (2007–2009). d p < 0.05 for difference when comparing patients with and without T2DM (2010–2012). e p < 0.05 for difference when comparing patients with and without T2DM (2013–2015). f p < 0.05 for difference when comparing patients with and without T2DM (total)
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Cardiovascular Diabetology

ISSN: 1475-2840