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Table 1 Clinical characteristics and in-hospital outcomes of hospitalized patients who underwent surgical aortic valve replacement (SAVR) in Spain from 2001 to 2015 according to T2DM status

From: Impact of type 2 diabetes mellitus in the utilization and in-hospital outcomes of surgical aortic valve replacement in Spain (2001–2015)

  T2DM 2001–2003 2004–2006 2007–2009 2010–2012 2013–2015 Total Trend
Number of SAVR Yes 1979 3001 3582 4637 5179 18,378 NA
No 9897 11,329 11,832 12,955 13,832 59,845 NA
Prevalence of T2DM Yes 16.7 20.9 23.2 26.4 27.2 23.5 < 0.001
Age, mean (SD)abcdef Yes 70.2 (7.5) 70.9 (7.4) 71.6 (7.6) 72.5 (7.7) 72.8 (7.8) 71.9 (7.7) < 0.001
No 67.8 (9.5) 69.1 (9.6) 69.7 (9.8) 70.7 (10.1) 71.0 (10.0) 69.8 (9.9) < 0.001
Female sex, n (%)abcdf Yes 943 (47.6) 1312 (43.7) 1525 (42.6) 1934 (41.7) 2035 (39.3) 7749 (42.2) < 0.001
No 3795 (38.3) 4382 (38.7) 4582 (38.7) 5172 (39.9) 5398 (39.0) 23,329 (38.9) 0.079
CCI, mean (SD)acef Yes 0.65 (0.5) 0.70 (0.6) 0.73 (0.7) 0.74 (0.6) 0.80 (0.7) 0.74 (0.7) < 0.001
No 0.59 (0.5) 0.67 (0.5) 0.69 (0.5) 0.73 (0.6) 0.76 (0.7) 0.70 (0.6) < 0.001
Mechanical SAVR, n (%)abcdef Yes 1384 (69.9) 1702 (56.7) 1747 (48.8) 1957 (42.2) 2045 (39.5) 8835 (48.1) < 0.001
No 7146 (72.2) 6909 (61.0) 6137 (51.9) 5952 (45.9) 5900 (42.6) 32,044 (53.5) < 0.001
Bioprosthetic SAVR, n (%)abcdef Yes 595 (30.1) 1299 (43.3) 1835 (51.2) 2680 (57.8) 3134 (60.5) 9543 (51.9) < 0.001
No 2751 (27.8) 4420 (39.0) 5695 (48.1) 7003 (54.1) 7932 (57.3) 27,801 (46.5) < 0.001
CABG, n (%)abcdef Yes 566 (28.6) 983 (32.8) 1133 (31.6) 1320 (28.5) 1432 (27.6) 5434 (29.6) < 0.001
No 1838 (18.6) 2348 (20.7) 2586 (21.9) 2745 (21.2) 2893 (20.9) 12,410 (20.8) < 0.001
Pacemaker implantation, n (%) Yes 77 (3.9) 121 (4.0) 189 (5.3) 193 (4.2) 234 (4.5) 814 (4.4) 0.419
No 337 (3.4) 439 (3.9) 623 (5.3) 520 (4.0) 568 (4.1) 2487 (4.1) 0.030
LOHS, mean (SD)abcef Yes 22.77 (16.6) 22.00 (21.1) 21.16 (18.0) 17.60 (13.7) 15.86 (12.9) 19.08 (16.4) < 0.001
No 20.41 (16.3) 19.89 (16.5) 19.48 (16.9) 17.64 (17.1) 16.36 (15.8) 18.59 (16.6) < 0.001
IHM, n (%)def Yes 176 (8.9) 230 (7.7) 254 (7.1) 226 (4.9) 201 (3.9) 1087 (5.9) < 0.001
No 773 (7.8) 895 (7.9) 833 (7.0) 799 (6.2) 701 (5.1) 4001 (6.7) < 0.001
  1. CABG, coronary artery bypass surgery; CCI, Charlson Comorbidity Index; LOHS, Length of hospital stay; IHM, in-hospital mortality, NA, not applicable
  2. ap < 0.05 for difference when comparing patients with and without T2DM (2001–2003). b p < 0.05 for difference when comparing patients with and without T2DM (2004–2006). c p < 0.05 for difference when comparing patients with and without T2DM (2007–2009). d p < 0.05 for difference when comparing patients with and without T2DM (2010–2012). e p < 0.05 for difference when comparing patients with and without T2DM (2013–2015). f p < 0.05 for difference when comparing patients with and without T2DM (total)