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Table 2 Comparison of gestational glucose tolerance groups at 3-years postpartum

From: Rising plasminogen activator inhibitor-1 and hypoadiponectinemia characterize the cardiometabolic biomarker profile of women with recent gestational diabetes

At 3-years postpartum

Normal GCT NGT

Abnormal GCT NGT

GIGT

GDM

P

BMI (kg/m2)

25.5 ± 4.5

25.3 ± 4.9

26.6 ± 4.8

26.8 ± 6.1

0.15

Waist circumference (cm)

88 ± 12

86 ± 12

89 ± 12

90 ± 13

0.15

A1c (%)

5.4 ± 0.3

5.5 ± 0.3

5.6 ± 0.3

5.6 ± 0.4

0.0001

Fasting glucose on OGTT (mmol/L)

4.6 ± 0.4

4.6 ± 0.5

4.8 ± 0.5

4.9 ± 0.6

< 0.0001

2-h glucose on OGTT (mmol/L)

5.5 ± 1.2

6.1 ± 1.7

6.6 ± 2.1

7.4 ± 2.2

< 0.0001

Current glucose tolerance status

< 0.0001

 Normal (%)

93.4

85.9

79.7

63.8

 

 Pre-diabetes/diabetes (%)

6.6

14.1

20.3

36.2

 

Adiponectin (μg/mL)

10.4 ± 4.6

10.1 ± 4.0

8.3 ± 3.6

8.6 ± 3.1

0.0003

Chemerin (ng/mL)

58.4 ± 14.0

59.7 ± 14.0

61.6 ± 13.7

59.9 ± 13.7

0.62

RBP-4 (mg/L)

39.7 ± 15.1

45.5 ± 18.4

42.2 ± 13.2

43.4 ± 18.0

0.16

CRP (mg/L)

1.1 (0.4–2.3)

0.9 (0.5–1.9)

1.0 (0.4–2.9)

1.5 (0.6–3.0)

0.09

PAI-1 (pg/mL)

7445 (6989–7724)

7366 (7109–7601)

7473 (7140–7654)

7446 (7193–7649)

0.43

  1. P-values refer to overall comparison across the 4 groups by either one-way analysis of variance or Kruskal–Wallis test for continuous variables, or either χ2 or Fisher exact test for categorical variables. Italic indicates P < 0.05