Table 1 Association of ACE2 SNPs with T2D in study participants
From: ACE2 polymorphisms associated with cardiovascular risk in Uygurs with type 2 diabetes mellitus
ACE2 SNPs | Non-diabetic (N/%) | Diabetic (N/%) | OR (95% CI)a | P-value | |
|---|---|---|---|---|---|
rs1978124 | |||||
 CC | 194 (71.3) | 137 (49.8) | 1.00 |  | |
 TT + CT | 78 (28.7) | 138 (50.2) | 2.24 (1.53–3.26) | < 0.001 | |
rs2048683 | |||||
 GG | 222 (81.6) | 171 (62.2) | 1.00 |  | |
 TT + GT | 50 (18.4) | 104 (37.8) | 3.07 (2.02–4.68) | < 0.001 | |
rs2074192 | |||||
 CC | 104 (38.2) | 136 (49.5) | 2.12 (1.43–3.13) | < 0.001 | |
 TT + CT | 168 (61.8) | 139 (50.5) | 1.00 |  | |
rs233575 | |||||
 CC + CT | 58 (21.3) | 112 (40.7) | 3.00 (1.99–4.51) | < 0.001 | |
 TT | 214 (78.7) | 163 (59.3) | 1.00 |  | |
rs4240157 | |||||
 CC + CT | 64 (23.5) | 124 (45.1) | 2.75 (1.87–4.04) | < 0.001 | |
 TT | 208 (76.5) | 151 (54.9) | 1.00 |  | |
rs4646156 | |||||
 AA + AT | 54 (19.9) | 104 (37.8) | 2.71 (1.79–4.10) | < 0.001 | |
 TT | 218 (80.1) | 171 (62.2) | 1.00 |  | |
rs4646188 | |||||
 CC + CT | 102 (37.5) | 64 (23.3) | 1.00 |  | |
 TT | 170 (62.5) | 211 (76.7) | 2.18 (1.47–3.22) | < 0.001 | |
rs879922 | |||||
 CC + CG | 128 (47.1) | 176 (64.0) | 1.78 (1.19–2.65) | 0.005 | |
 GG | 144 (52.9) | 271 (36.0) | 1.00 |  | |