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Table 1 Association of ACE2 SNPs with T2D in study participants

From: ACE2 polymorphisms associated with cardiovascular risk in Uygurs with type 2 diabetes mellitus

ACE2 SNPs Non-diabetic (N/%) Diabetic (N/%) OR (95% CI)a P-value
rs1978124
 CC 194 (71.3) 137 (49.8) 1.00  
 TT + CT 78 (28.7) 138 (50.2) 2.24 (1.53–3.26) < 0.001
rs2048683
 GG 222 (81.6) 171 (62.2) 1.00  
 TT + GT 50 (18.4) 104 (37.8) 3.07 (2.02–4.68) < 0.001
rs2074192
 CC 104 (38.2) 136 (49.5) 2.12 (1.43–3.13) < 0.001
 TT + CT 168 (61.8) 139 (50.5) 1.00  
rs233575
 CC + CT 58 (21.3) 112 (40.7) 3.00 (1.99–4.51) < 0.001
 TT 214 (78.7) 163 (59.3) 1.00  
rs4240157
 CC + CT 64 (23.5) 124 (45.1) 2.75 (1.87–4.04) < 0.001
 TT 208 (76.5) 151 (54.9) 1.00  
rs4646156
 AA + AT 54 (19.9) 104 (37.8) 2.71 (1.79–4.10) < 0.001
 TT 218 (80.1) 171 (62.2) 1.00  
rs4646188
 CC + CT 102 (37.5) 64 (23.3) 1.00  
 TT 170 (62.5) 211 (76.7) 2.18 (1.47–3.22) < 0.001
rs879922
 CC + CG 128 (47.1) 176 (64.0) 1.78 (1.19–2.65) 0.005
 GG 144 (52.9) 271 (36.0) 1.00  
  1. aAfter adjustment for nationality, gender, age, smoking and BMI