Early vascular parameters in the micro- and macrocirculation in type 2 diabetes

Table 2 Parameters in the micro- and macrocirculation

	Non-T2DM-subjects (n = 54)	T2DM-subjects (n = 111)	Unadjusted p-value	Adjusted p-value (model 1)	Adjusted p-value (model 2)
Retinal parameters
ICD (µm)	20.8 ± 3.5	23.9 ± 5.1	< 0.001	< 0.001	0.001
RCF (AU)	310.4 ± 55.1	297.8 ± 72.9	0.15	0.35	0.72
WLR	0.35 ± 0.08	0.38 ± 0.11	0.04	0.67	0.90
Renal parameters
eGFR (ml/min/1.73 m²)	95.9 ± 17.3	91.7 ± 9.9	0.10	< 0.001	< 0.001
UACR (mg/g)	7.9 ± 7.5	21.3 ± 86.6	< 0.001	0.55	0.91
Vascular stiffness parameters of large arteries (mmHg)
cSBP	106.7 ± 12.4	119.5 ± 12.9	< 0.001	0.37	0.81
cPP	34.8 ± 10.6	41.8 ± 11.7	0.001	0.31	< 0.001

Data are given as mean ± SD
ICD intercapillary distance, RCF retinal capillary flow, WLR wall to lumen ratio, eGFR estimated glomerular filtration rate, UACR urinary albumin creatinine ratio, cSBP central systolic blood pressure, cPP central pulse pressure, model 1 p-values are adjusted for age and gender, model 2 p-values are adjusted for age, gender, BMI, fasting plasma glucose, HbA1c and serum HDL-cholesterol

ISSN: 1475-2840