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Table 2 Subgroup CVD risk factor characteristics

From: The role of physical activity in the development of first cardiovascular disease event: a tree-structured survival analysis of the Danish ADDITION-PRO cohort

Subgroups 1 2 3 4 5 6 7 8 9
N 103 20 29 339 22 21 207 229 479
Events (%) 16 (15.5) 1 (5.0) 0 (0.0) 14 (4.1) 9 (40.9) 2 (9.5) 22 (10.6) 43 (18.8) 94 (19.6)
Male sex (%) 45 (43.7) 8 (40.0) 16 (55.2) 170 (50.1) 16 (72.7) 10 (47.6) 0 (0.0) 229 (100.0) 247 (51.6)
Age (years) 64.4 [59.9, 66.3] 60.0 [53.5, 62.7] 62.2 [57.3, 66.0] 62.0 [57.8, 65.3] 66.0 [63.6, 68.3] 63.3 [62.1, 66.2] 63.1 [58.5, 65.7] 63.3 [59.6, 66.0] 72.5 [70.6, 75.0]
Smoking (% yes) 13 (12.6) 2 (10.0) 6 (20.7) 34 (10.0) 4 (18.2) 1 (4.8) 44 (21.3) 61 (26.6) 62 (12.9)
Employed (% yes) 56 (54.4) 15 (75.0) 15 (51.7) 200 (59.0) 9 (40.9) 11 (52.4) 86 (41.5) 141 (61.6) 68 (14.2)
Body mass index (kg/m2) 26.1 [23.3, 28.9] 23.3 [22.0, 25.8] 24.5 [22.6, 27.3] 26.2 [23.6, 29.3] 29.2 [26.0, 30.7] 27.8 [25.0, 31.0] 29.0 [25.4, 33,0] 29.1 [26.7, 31.7] 26.5 [24.2, 29.5]
Systolic blood pressure (mmHg) 129 (14) 127 (15) 130 (14) 127 (14) 167 (8) 167 (12) 131 (17) 137 (16.3) 135 (17.0)
Diastolic blood pressure (mmHg) 81 (9) 79 (11) 82 (9) 81 (9) 100 (6) 95 (11) 83.2 (9.8) 84.6 (10.1) 80.1 (10.3)
Total cholesterol (mmol/l) 5.7 (0.8) 5.4 (0.7) 5.8 (1.0) 5.4 (1.0) 5.8 (0.9) 6.0 (1.0) 5.3 (1.0) 5.1 (1.0) 5.3 (1.1)
High density lipoprotein cholesterol (mmol/l) 1.5 [1.2, 2.0] 1.5 [1.4, 2.2] 1.7 [1.4, 2.0] 1.6 [1.3, 1.8] 1.3 [1.0, 1.2] 1.5 [1.4, 2.2] 1.5 [1.1, 1.8] 1.1 [1.0, 1.5] 1.6 [1.2, 1.8]
Low density lipoprotein cholesterol (mmol/l) 3.3 (0.7) 3.1 (0.5) 3.5 (0.9) 3.4 (0.9) 3.7 (0.7) 3.6 (0.6) 3.2 (1.0) 3.1 (1.1) 3.3 (1.0)
Triacylglycerol (mmol/l) 1.0 [0.9, 1.3] 0.7 [0.5, 1.3] 1.1 [0.6, 1.5] 1.0 [0.8, 1.3] 1.5 [1.1, 2.3] 0.8 [0.7, 1.0] 1.2 [1.0, 1.8] 1.4 [1.1, 2.1] 1.1 [0.7, 1.5]
HbA1c (%) 5.3 [5.3, 5.5] 5.4 [5.4, 5.5] 5.4 [5.3, 5.6] 5.4 [5.2, 5.5] 5.6 [5.3, 5.6] 5.4 [5.4, 5.5] 6.0 [5.7, 6.1] 6.0 [5.8, 6.3] 5.8 [5.4, 6.0]
Albumin creatinine ratio 29 (20) 38.3 (16.7) 27.5 (19.6) 105.6 (21.0) 76.0 (44.0) 74.2 (43.2) 77.2 (46.4) 84.3 (40.1) 79.2 (43.3)
Estimated glomerular filtration rate (ml/min/1.73m2) 80.0 [72.0, 89.0] 74.0 [70.8, 75.4] 88.0 [84.0, 93.0] 81.0 [72.0, 89.0] 77.4 [69.3, 88.0] 78.0 [73.0, 89.0] 82.0 [71.0, 91.4] 86.0 [76.0, 92.0] 74.0 [66.0, 84.0]
Any anti-diabetic drug (%) 0 (0.0) 0 (0.0) 0 (0.0) 6 (1.8) 1 (4.5) 0 (0.0) 22 (10.8) 26 (11.4) 18 (3.8)
Any anti-hypertensive drug (%) 38 (36.9) 5 (25.0) 4 (13.8) 98 (29.3) 9 (40.9) 10 (47.6) 98 (48.0) 96 (41.9) 216 (45.5)
Any lipid-lowering drug (%) 15 (14.6) 2 (10.0) 2 (6.9) 39 (11.6) 4 (18.2) 1 (4.8) 80 (39.2) 81 (35.4) 134 (28.2)
Aspirin (%) 9 (8.7) 0 (0.0) 1 (3.4) 26 (7.8) 4 (18.2) 5 (23.8) 36 (17.6) 43 (18.8) 85 (17.9)
  1. Data are median [IQR], mean (SD) or n (%)
  2. HbA1c glycated hemoglobin A1c
  3. * For p-value < 0.05 and ** for < 0.01
  4. aEmployed includes the self-employed. Out of work includes the unemployed, housewives, retired individuals and individuals receiving government provisions