Table 2 Subgroup CVD risk factor characteristics

N

103

20

29

339

22

21

207

229

479

Events (%)

16 (15.5)

1 (5.0)

0 (0.0)

14 (4.1)

9 (40.9)

2 (9.5)

22 (10.6)

43 (18.8)

94 (19.6)

Male sex (%)

45 (43.7)

8 (40.0)

16 (55.2)

170 (50.1)

16 (72.7)

10 (47.6)

0 (0.0)

229 (100.0)

247 (51.6)

Age (years)

64.4 [59.9, 66.3]

60.0 [53.5, 62.7]

62.2 [57.3, 66.0]

62.0 [57.8, 65.3]

66.0 [63.6, 68.3]

63.3 [62.1, 66.2]

63.1 [58.5, 65.7]

63.3 [59.6, 66.0]

72.5 [70.6, 75.0]

Smoking (% yes)

13 (12.6)

2 (10.0)

6 (20.7)

34 (10.0)

4 (18.2)

1 (4.8)

44 (21.3)

61 (26.6)

62 (12.9)

Employed (% yes)

56 (54.4)

15 (75.0)

15 (51.7)

200 (59.0)

9 (40.9)

11 (52.4)

86 (41.5)

141 (61.6)

68 (14.2)

Body mass index (kg/m²)

26.1 [23.3, 28.9]

23.3 [22.0, 25.8]

24.5 [22.6, 27.3]

26.2 [23.6, 29.3]

29.2 [26.0, 30.7]

27.8 [25.0, 31.0]

29.0 [25.4, 33,0]

29.1 [26.7, 31.7]

26.5 [24.2, 29.5]

Systolic blood pressure (mmHg)

129 (14)

127 (15)

130 (14)

127 (14)

167 (8)

167 (12)

131 (17)

137 (16.3)

135 (17.0)

Diastolic blood pressure (mmHg)

81 (9)

79 (11)

82 (9)

81 (9)

100 (6)

95 (11)

83.2 (9.8)

84.6 (10.1)

80.1 (10.3)

Total cholesterol (mmol/l)

5.7 (0.8)

5.4 (0.7)

5.8 (1.0)

5.4 (1.0)

5.8 (0.9)

6.0 (1.0)

5.3 (1.0)

5.1 (1.0)

5.3 (1.1)

High density lipoprotein cholesterol (mmol/l)

1.5 [1.2, 2.0]

1.5 [1.4, 2.2]

1.7 [1.4, 2.0]

1.6 [1.3, 1.8]

1.3 [1.0, 1.2]

1.5 [1.4, 2.2]

1.5 [1.1, 1.8]

1.1 [1.0, 1.5]

1.6 [1.2, 1.8]

Low density lipoprotein cholesterol (mmol/l)

3.3 (0.7)

3.1 (0.5)

3.5 (0.9)

3.4 (0.9)

3.7 (0.7)

3.6 (0.6)

3.2 (1.0)

3.1 (1.1)

3.3 (1.0)

Triacylglycerol (mmol/l)

1.0 [0.9, 1.3]

0.7 [0.5, 1.3]

1.1 [0.6, 1.5]

1.0 [0.8, 1.3]

1.5 [1.1, 2.3]

0.8 [0.7, 1.0]

1.2 [1.0, 1.8]

1.4 [1.1, 2.1]

1.1 [0.7, 1.5]

HbA1c (%)

5.3 [5.3, 5.5]

5.4 [5.4, 5.5]

5.4 [5.3, 5.6]

5.4 [5.2, 5.5]

5.6 [5.3, 5.6]

5.4 [5.4, 5.5]

6.0 [5.7, 6.1]

6.0 [5.8, 6.3]

5.8 [5.4, 6.0]

Albumin creatinine ratio

29 (20)

38.3 (16.7)

27.5 (19.6)

105.6 (21.0)

76.0 (44.0)

74.2 (43.2)

77.2 (46.4)

84.3 (40.1)

79.2 (43.3)

Estimated glomerular filtration rate (ml/min/1.73m²)

80.0 [72.0, 89.0]

74.0 [70.8, 75.4]

88.0 [84.0, 93.0]

81.0 [72.0, 89.0]

77.4 [69.3, 88.0]

78.0 [73.0, 89.0]

82.0 [71.0, 91.4]

86.0 [76.0, 92.0]

74.0 [66.0, 84.0]

Any anti-diabetic drug (%)

0 (0.0)

0 (0.0)

0 (0.0)

6 (1.8)

1 (4.5)

0 (0.0)

22 (10.8)

26 (11.4)

18 (3.8)

Any anti-hypertensive drug (%)

38 (36.9)

5 (25.0)

4 (13.8)

98 (29.3)

9 (40.9)

10 (47.6)

98 (48.0)

96 (41.9)

216 (45.5)

Any lipid-lowering drug (%)

15 (14.6)

2 (10.0)

2 (6.9)

39 (11.6)

4 (18.2)

1 (4.8)

80 (39.2)

81 (35.4)

134 (28.2)

Aspirin (%)

9 (8.7)

0 (0.0)

1 (3.4)

26 (7.8)

4 (18.2)

5 (23.8)

36 (17.6)

43 (18.8)

85 (17.9)