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Table 1 Baseline clinical characteristics
| Variables | All patients | Low MAGE | High MAGE | p-value |
|---|---|---|---|---|
| (n = 417) | (n = 268) | (n = 149) | ||
| Age, years | 66 (56–74) | 66 (56–74) | 68 (58–75) | 0.275 |
| Male, n (%) | 348 (83) | 219 (82) | 129 (85) | 0.201 |
| Body mass index, kg/m2 | 26.8 (22.1–29.5) | 24.5 (22.4–27.3) | 23.9 (21.8–26.1) | 0.010 |
| STE-ACS, n (%) | 292 (70) | 191 (71) | 101 (68) | 0.457 |
| Killip class > 1, n (%) | 74 (18) | 40 (15) | 34 (23) | 0.042 |
| Infarct-related artery, n (%) | ||||
| Left anterior descending coronary artery, n (%) | 229 (55) | 150 (56) | 79 (53) | 0.562 |
| Left circumflex coronary artery, n (%) | 45 (11) | 29 (11) | 16 (11) | 0.979 |
| Right coronary artery, n (%) | 143 (34) | 89 (33) | 54 (36) | 0.532 |
| Multivessel disease, n (%) | 176 (42) | 99 (37) | 77 (52) | 0.004 |
| GRACE score > 140, n (%) | 212 (51) | 125 (47) | 87 (58) | 0.022 |
| Hypertension, n (%) | 255 (61) | 155 (58) | 100 (67) | 0.063 |
| Hypercholesteremia, n (%) | 160 (38) | 109 (41) | 51 (34) | 0.195 |
| Systolic blood pressure on admission, mmHg | 150 (125–170) | 149 (125–167) | 153 (124–177) | 0.806 |
| Heart rate on admission, bpm | 76 (64–88) | 76 (64–88) | 76 (65–90) | 0.575 |
| Laboratory data | ||||
| Cre on admission, mg/dl | 0.84 (0.72–1.00) | 0.84 (0.73–0.98) | 0.83 (0.71–1.02) | 0.720 |
| eGFR on admission, % | 67.9 (56.3–81.1) | 67.3 (55.9–80.0) | 70.4 (56.3–83.1) | 0.091 |
| Peak level of CPK, IU/l | 1129 (250–2864) | 1130 (243–2870) | 1129 (265–2838) | 0.696 |
| BNP during stable phase, pg/ml | 89.2 (35.5–192.7) | 80.4 (35.4–171.4) | 101.3 (37.7–209.1) | 0.007 |
| hs-CRP during stable phase > 0.1355 mg/dl, n (%) | 185 (44) | 115 (43) | 70 (47) | 0.393 |
| Lipid profile on admission | ||||
| LDL cholesterol, mg/dl | 128 (105–152) | 131 (108–155) | 124 (102–148) | 0.114 |
| HDL cholesterol, mg/dl | 44 (37–52) | 43 (37–51) | 45 (37–52.5) | 0.131 |
| Triglycerides, mg/dl | 118 (75–185) | 124 (78–197) | 113 (70–162) | 0.125 |
| Medication on discharge, n (%) | ||||
| ACE-I or ARB | 334 (80) | 210 (78) | 124 (83) | 0.233 |
| β-blocker | 275 (66) | 175 (65) | 100 (67) | 0.708 |
| Statin | 400 (96) | 258 (96) | 142 (95) | 0.632 |
