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Table 1 Clinical baseline characteristic and medication data

From: Biodegradable polymer drug-eluting stents versus second-generation drug-eluting stents in patients with and without diabetes mellitus: a single-center study

Characteristics DM P No-DM P
G2‑DES N = 1862 BP‑DES N = 421 G2‑DES N = 4232 BP‑DES N = 1151
Age (years) 59.0 ± 9.7 59.7 ± 9.7 0.814 57.5 ± 10.6 58.5 ± 10.4 0.241
Sex (male) 1411 (75.8) 314 (74.6) 0.607 3307 (78.1) 872 (75.8) 0.085
BMI (kg/m2) 26.3 ± 3.1 26.2 ± 3.1 0.595 25.8 ± 3.2 25.8 ± 3.1 0.754
LVEF (%) 62.7 ± 7.5 61.8 ± 7.9 0.207 63.1 ± 7.2 61.8 ± 7.9 0.262
Hypertension (n, %) 1284 (69.0) 314 (74.6) 0.023 2545 (60.1) 726 (63.1) 0.070
Hyperlipidemia (n, %) 1383 (74.3) 306 (72.7) 0.502 2754 (65.1) 717 (62.3) 0.080
Current smoker (n, %) 1014 (54.5) 240 (57.0) 0.342 2414 (57.0) 685 (59.5) 0.132
Family history (n, %) 486 (26.1) 102 (24.2) 0.427 1047 (24.7) 264 (22.9) 0.206
Stroke history (n, %) 231 (12.4) 60 (14.3) 0.305 369 (8.7) 118 (10.3) 0.108
PAD (n, %) 62 (3.3) 19 (4.5) 0.236 99 (2.3) 18 (1.6) 0.110
COPD (n, %) 43 (2.3) 10 (2.4) 0.935 98 (2.3) 26 (2.3) 0.158
OMI (n, %) 348 (18.7) 101 (24.0) 0.013 749 (17.7) 211 (18.3) 0.619
Previous PCI (n, %) 480 (25.8) 133 (31.6) 0.015 976 (23.1) 247 (21.5) 0.250
Previous CABG (n, %) 82 (4.4) 21 (5.0) 0.602 163 (3.9) 25 (2.2) 0.006
Serum creatinine (ml/min) 74.9 ± 16.7 76.9 ± 17.8 0.233 75.4 ± 15.3 76.2 ± 15.5 0.425
HbA1c (%) 7.8 ± 1.4 7.9 ± 1.4 0.772 6.1 ± 0.6 6.1 ± 0.6 0.744
Clinical presentation (n, %)
 Stable angia 796 (42.7) 175 (41.6) 0.658 1631 (38.5) 432 (37.5) 0.533
 NSTE-ACS 857 (46.0) 189 (44.9) 0.674 2026 (47.9) 534 (46.4) 0.373
 STEMI 209 (11.2) 57 (13.5) 0.181 574 (13.6) 185 (16.1) 0.030
Medication (cases, %)
 Aspirin 1841 (98.9) 419 (99.5) 0.289 4173 (98.6) 1140 (99.0) 0.244
 Clopidogrel 1840 (98.8) 416 (98.8) > 0.999 4159 (98.3) 1138 (98.9) 0.153
 DAPT 1821 (97.8) 415 (98.6) 0.311 4104 (97.0) 1131 (98.3) 0.018
 GP IIIb/IIa inhibitors 206 (11.1) 62 (14.7) 0.035 500 (11.8) 217 (18.9) < 0.001
 Statin 1774 (95.3) 406 (96.4) 0.299 4071 (96.2) 1104 (95.9) 0.663
 β‑blocker 1705 (91.6) 403 (95.7) 0.004 3782 (89.4) 1021 (88.7) 0.521
 Calcium antagonist 956 (51.3) 221 (52.5) 0.669 2002 (47.3) 518 (45.0) 0.165
 Nitrate 1807 (97.0) 414 (98.3) 0.141 4130 (97.6) 1127 (97.9) 0.518
 PPI 341 (18.3) 79 (18.8) 0.829 836 (19.8) 266 (23.1) 0.012
Therapeutic status for DM (n, %)
 Diet and exercise 342 (18.4) 76 (18.1) 0.880
 Antidiabetic agents 836 (44.9) 209 (49.6) 0.078
 Insulin 494 (26.5) 104 (24.7) 0.441
 Insulin and antidiabetic agents 190 (10.2) 32 (7.6) 0.104
  1. DM diabetes mellitus, BP-DES biodegradable polymer drug-eluting stents, G2-DES second generation drug-eluting stents, BMI body mass index, LVEF left ventricular ejection fraction, PAD peripheral arterial disease, COPD chronic obstructive pulmonary disease, OMI old myocardial infarction, PCI percutaneous coronary intervention, CABG coronary artery bypass grafting, NSTE-ACS non-ST-segment elevation acute coronary syndrome, STEMI ST-segment elevation myocardial infarction, DAPT dual antiplatelet treatment, GP glycoprotein, PPI proton pump inhibitors