Explanatory variable

LV mass

LVEF

GLS

E/é


Univariable

Multivariable model R^{2} = 0.23

Univariable

Multivariable model R^{2} = 0.19

Univariable

Multivariable model R^{2} = 0.24

Univariable

Multivariable model R^{2} = 0.18


β_{1}, R^{2}

B

β_{1}, R^{2}

B

β_{1}, R^{2}

B

β_{1}, R^{2}

B


Demographic data

Age, years

0.4, 0.00
 
0.08, 0.00
 
− 0.02, 0.00
 
0.14*, 0.02
 
Gender = female

− 12.8***, 0.06

− 8.1**

− 0.04, 0.00
 
− 0.91**, 0.03

− 0.8*

1.08**, 0.02

1.4***

Smoker/former smoker

4.2, 0.01
 
− 0.8, 0.00
 
− 0.27, 0.00
 
− 0.30, 0.00
 
BMI, kg/m^{2}

1.1***, 0.05

1.1***

− 0.7***, 0.16

− 0.7***

0.17***, 0.10

0.2***

0.13**, 0.03
 
Medical history

Diabetes duration, years

− 0.1, 0.00
 
0.09, 0.00
 
− 0.01, 0.00
 
0.05, 0.00
 
Angina pectoris

17.9***,0.04
 
− 4.6**, 0.02
 
2.7***, 0.00

1.6***

1.22, 0.01
 
Myocardial infarction

13.2*, 0.02
 
− 3.3, 0.01
 
1.7**, 0.02
 
0.74, 0.00
 
Coronary revascularization

16.2**, 0.02
 
− 3.0, 0.01
 
1.67**, 0.03
 
− 0.37, 0.00
 
Heart failure

20.8*, 0.01
 
− 12.2***, 0.05

− 9.6***

4.3***, 0.05

2.5**

4.05**, 0.03
 
Hypertension

3.8, 0.01
 
1.6, 0.01
 
− 0.13, 0.00
 
0.60, 0.01
 
Medication

Loop diuretics

6.8, 0.00
 
− 5.8***, 0.03
 
1.9**, 0.03
 
2.7***, 0.04

2.1**

Statins

− 3.3, 0.00
 
− 0.59, 0.00
 
0.26, 0.00
 
0.28, 0.00
 
ACEI and/or ARB

4.2, 0.01
 
0.38, 0.00
 
0.00, 0.00
 
0.60, 0.01
 
Calcium channel blocker

12.9***, 0.04

6.6*

− 0.24, 0.00
 
0.27, 0.00
 
0.95*, 0.01
 
βBlocker

12.8***, 0.06

9.4***

0.33, 0.00
 
− 0.01, 0.00
 
1.02**, 0.02

0.8

Laboratory analyses

HbA1c, %

0.9, 0.00
 
− 1.2**, 0.02
 
0.55***, 0.04

0.4**

0.33, 0.01
 
Triglycerides, mmol/L

1.2, 0.00
 
− 1.4*, 0.01
 
0.43*, 0.01
 
0.38*, 0.01

0.4*

LDLC, mmol/L

− 1.2, 0.00
 
− 0.32, 0.00
 
− 0.05, 0.00
 
− 0.15, 0.00
 
Microalbuminuria

14.8***, 0.05

8.4**

− 1.8, 0.01
 
0.49, 0.00
 
1.55**, 0.03

1.1*

Creatinine, µmol/L

0.3***, 0.04

0.2*

0.02, 0.00
 
0.01, 0.00
 
0.00, 0.00
 
GFR, mL/min/1.73 m^{2}

− 0.1, 0.00
 
− 0.03, 0.00
 
0.00, 0.00
 
− 0.01, 0.00
 
Blood pressure (mmHg)

Systolic blood pressure

0.3***, 0.03

0.2*

− 0.02, 0.00
 
0.02**, 0.02
 
0.06***, 0.07

0.06***

Diastolic blood pressure

0.2, 0.01
 
− 0.05, 0.00
 
0.06***, 0.03

0.04**

0.04*, 0.01
 
 Results from univariable regression Y = β_{0} + β_{1}*X + ε. Results are presented as estimated regression parameters β_{1} and pvalues (* p < 0.05, ** p < 0.01 and *** p < 0.001) for parameters and R^{2}. Hypothesis tested H_{0}: β_{0} and β_{1} = 0 against H_{1}: β_{0} and β_{1} ≠ 0. Note that the β_{0} term is not presented in the table. Final results of multivariable linear regression analysis Y = Β X + ε of LV mass, LVEF and E/é. B is the estimated vector of regression parameters in the multivariable model. ε represents the errorterm in the model. Results are presented as estimated regression parameters, pvalues for the parameters, and R^{2}, the explained proportion of variation in the outcome variable by the explanatory variables. LV mass are indexed by body surface area. See abbreviations as in Tables 1 and 2