Fig. 3From: Canagliflozin attenuates the progression of atherosclerosis and inflammation process in APOE knockout miceCanagliflozin/vehicle oral administration effect on heart rate of APOE(−/−) mice. a 5 weeks of canagliflozin intervention led to significant reduction of heart rate (**P < 0.01) while no significant difference was observed in the control group. b Heart rate changes from baseline were significantly different between Cana- and control-groups (*P < 0.05)Back to article page