Beneficial effects of cherry consumption as a dietary intervention for metabolic, hepatic and vascular complications in type 2 diabetic rats

Table 1 Characteristics of rats after 4 months of experimental period

Variables	ND	HFHF	HFHF/ND	HFHF/NDCherry	HFHFCherry
Physiological variables
Weight gain from 2 to 4 months (g)	63.4 ± 6.9	97.5 ± 4.60*	13 ± 12.14***^$$$	36.12 ± 9.5^$$$	95.12 ± 12.0
Final body weight (g)	558 ± 15.3	628 ± 12.6**	570 ± 13.4^$	581 ± 12.2^$	652.95 ± 20.71***
Body mass index (BMI) (g/cm²)	0.78 ± 0.003	0.86 ± 0.02*	0.76 ± 0.02^$	0.79 ± 0.03	0.88 ± 0.05*
Abdominal circumference (cm)	22.14 ± 0.59	24.9 ± 0.78*	22.08 ± 1.34^$	23.5 ± 0.62	25.25 ± 0.98*
Abdominal fat (g) (% vs. total weight)	12.22 ± 1.74	34.60 ± 1.38***	18.33 ± 3.39^$$$	17.92 ± 2.43^$$$	29.85 ± 3.57***
Abdominal fat (g) (% vs. total weight)	2.17 ± 0.27	4.37 ± 0.96***	3.17 ± 0.49^$$$	3.07 ± 0.40^$$$	4.58 ± 0.52***
Plasmatic lipidic profile
Fasting leptin (ng/mL)	13.23 ± 0.99	37.24 ± 5.39***	15.88 ± 1.08^$$$	20.77 ± 13.87^$$	51.26 ± 3.96***^$$
Total cholesterol (mM)	1.37 ± 0.12	2.21 ± 0.30**	1.71 ± 0.25	1.52 ± 0.16^$	2.86 ± 0.29***
Triglycerides (μM)	805.2 ± 175.2	1523 ± 184.6**	878 ± 199.7^$	650.2 ± 164.7^$$	1313 ± 189.4***^$$$
Free fatty acids (μmol/L)	82.11 ± 10.64	234.4 ± 29.39***	155.3 ± 14.12*^$$	130 ± 11.67*^$	354 ± 85.71***
Plasmatic oxidative profile
Lipid peroxide, TBARS (μM malondialdehyde)	35 ± 1.14	62.81 ± 8.86*	34.7 ± 0.91^$$$	33.41 ± 2.08^$$$	52.2 ± 9.54*
Total antioxidante capacity (mM trolox equivalent)	5.75 ± 0.18	5.75 ± 1.167	5.99 ± 0.131	6.62 ± 0.086*^$	4.36 ± 0.492**^$$

Experiments were performed six times
* Significant difference vs. ND; $ vs. HFHF; * and $ : P < 0.05; ** and $$ : P < 0.01; *** and $$$ : P < 0.001

ISSN: 1475-2840