|
SNP
|
Genotype distributiona
|
Additive model
|
Dominant model
|
Recessive model
|
|---|
|
T2DM (n = 68)
|
T2DM + CVD (n = 68)
|
OR (95% CI)
|
p
|
OR (95% CI)
|
p
|
OR (95% CI)
|
p
|
|---|
|
ANGPTL8 rs2278426
|
|
C/C
|
53 (78)
|
62 (91.2)
|
1.0 (reference)
|
–
| | | | |
|
C/T
|
12 (17.6)
|
5 (7.4)
|
2.8 (0.92–8.48)
|
0.15
|
0.34 (0.12–0.94)
|
0.05
|
0.32 (0.03–3.1)
|
0.6
|
|
T/T
|
3 (4.4)
|
1 (1.4)
|
3.50 (0.35–34.74)
| |
(C/C vs. C/T + T/T)
|
(C/C + C/T vs. T/T)
|
|
†Allele C
|
118 (86.7)
|
129 (96.3)
|
2.8 (1.13–6.97)
|
0.03*
| | |
|
Allele T
|
18 (13.3)
|
7 (3.7)
| | | | |
|
CETP rs708272
|
|
GG
|
30 (44)
|
32 (47.1)
|
1.0
|
–
| | |
|
GA
|
32 (47)
|
26 (38.2)
|
0.7(0.37–1.56)
|
0.4
|
0.88 (0.45–1.74)
|
0.8
|
1.78 (0.60–5.21)
|
0.4
|
|
AA
|
6 (9)
|
10 (14.7)
|
0.6 (0.20–1.97)
| |
(G/G/vs. G/A + A/A)
|
(G/G + G/A vs. A/A)
|
|
Allele G
|
92 (67.6)
|
90 (66.2)
|
1.06 (0.64–1.77)
|
0.89
| | |
|
Allele A
|
44 (32.4)
|
46 (33.8)
| | | | |
|
NOS3 rs1799983
|
|
GG
|
44 (67.4)
|
41 (60.3)
|
1.0 (reference)
|
–
| | |
|
GT
|
20 (29.4)
|
24 (35.3)
|
0.7 (0.37–1.61)
|
0.7
|
0.82 (0.41–1.66)
|
0.7
|
1.35 (0.29–6.29)
|
1.0
|
|
TT
|
4 (5.9)
|
3 (4.4)
|
1.37 (0.29–6.39)
| |
(G/G vs. G/T + T/T)
|
(G/G +G/T vs. T/T)
|
|
Allele G
|
108 (79.4)
|
106 (78)
|
0.91 (0.51–1.63)
|
0.88
| | |
|
Allele T
|
28 (20.6)
|
30 (22)
| | | | |
- * significant p
- †Alleles frequency calculated in 2N
- aData shown as number of subjects (%)
