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Table 4 Association of NOS3, ANGPTL8 and CETP SNPs with CVD

From: Interaction between endothelial nitric oxide synthase rs1799983, cholesteryl ester-transfer protein rs708272 and angiopoietin-like protein 8 rs2278426 gene variants highly elevates the risk of type 2 diabetes mellitus and cardiovascular disease

Gene SNP Cases MAF Controls MAF p OR (95% CI)
NOS3 rs1799983 22.0 8.0 0.0001* 3.08 (1.70–5.60)
ANGPTL8 rs2278426 5.1 7.4 0.28 0.55 (0.21–1.42)
CETP rs708272 33.8 41 0.9 1.0 (0.64–1.54)
  1. MAF minor allele frequency (defined based on frequency in controls)
  2. * Significant p