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Table 4 Association of NOS3, ANGPTL8 and CETP SNPs with CVD

From: Interaction between endothelial nitric oxide synthase rs1799983, cholesteryl ester-transfer protein rs708272 and angiopoietin-like protein 8 rs2278426 gene variants highly elevates the risk of type 2 diabetes mellitus and cardiovascular disease

Gene

SNP

Cases MAF

Controls MAF

p

OR (95% CI)

NOS3

rs1799983

22.0

8.0

0.0001*

3.08 (1.70–5.60)

ANGPTL8

rs2278426

5.1

7.4

0.28

0.55 (0.21–1.42)

CETP

rs708272

33.8

41

0.9

1.0 (0.64–1.54)

  1. MAF minor allele frequency (defined based on frequency in controls)
  2. * Significant p
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Cardiovascular Diabetology

ISSN: 1475-2840