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Table 1 Demographic, clinical and biochemical data of the studied participants

From: Interaction between endothelial nitric oxide synthase rs1799983, cholesteryl ester-transfer protein rs708272 and angiopoietin-like protein 8 rs2278426 gene variants highly elevates the risk of type 2 diabetes mellitus and cardiovascular disease

Variable

Controls (n = 136)

T2DM (n = 68)

T2DM + CVD (n = 68)

Age (years)

52.3 ± 2.5

51.8 ± 4.3

55.3 ± 5.7

Sex (male/female)

76/60

35/33

42/26

BMI (kg/m2)

26.1 ± 3.8

27.2 ± 2.7*

27.6 ± 2.2**

SBP (mmHg)

112 ± 8.5

125 ± 12

141 ± 20**,†

DBP (mmHg)

74 ± 7.5

87 ± 12

88 ± 10**,†

Hypertension (%)

–

30

92†

Smokers (%)

8

5.8

11.8†

Diabetes duration (years)

–

7.5 ± 4.5

12.5 ± 3.4†

FPG (mg/dL)

82 ± 7.5

135 ± 59*

166 ± 61**

HbA1c (%)

5.7 ± 0.5

6.8 ± 2.1*

6.9 ± 1.9**

TG (mg/dL)

127 ± 31

155 ± 70*

161 ± 56**,†

TC (mg/dL)

165 ± 20

178 ± 51*

200 ± 45**,†

LDL-C (mg/dL)

100 ± 22

120 ± 35.5*

126 ± 30**,†

HDL-C (mg/dL)

51.8 ± 7.9

48.5 ± 10.8*

44.1 ± 12.2**,†

  1. BMI body mass index, SBP systolic blood pressure, DBP diastolic blood pressure, FPG fasting plasma glucose, HbA1c hemoglobin A1C, TG triglyceride, TC total cholesterol, LDL-C low density lipoprotein cholesterol, HDL-C high density lipoprotein cholesterol
  2. * Significant p in comparison between controls and T2DM
  3. ** Significant p in comparison between controls and T2DM + CVD
  4. †Significant p in comparison between T2DM and T2DM + CVD