Table 1 Animal characteristics and laboratory parameters

N

12

7

6

22

13

15

BW (g)

305.3 ± 3.8

281.3 ± 3.3*

248.3 ± 8.1*

299.9 ± 3.1

282.8 ± 5.0*^†

263.5 ± 4.2*^†

LV W/TL (g/mm)

14.8 ± 0.1

13.4 ± 0.1*

12.2 ± 0.3*

15.9 ± 0.2*

15.0 ± 0.2^†

14.1 ± 0.4^†

Lung W/TL (g/mm)

27.4 ± 0.5

26.8 ± 0.3

24.7 ± 0.4

43.7 ± 3.9*

40.3 ± 4.4*

54.2 ± 5.0*^†

UG (mmol/l)

0.34 ± 0.07

316.0 ± 34.3*

256.2 ± 66.6*

0.21 ± 0.03

235.0 ± 10.3*^†

205.2 ± 21.6*^†

Fructosamine (μM)

141.8 ± 3.3

126.2 ± 2.4*

129.2 ± 2.8*

121.5 ± 3.3*

122.5 ± 2.0*

130.8 ± 4.4*^†

ANP: RPL13a mRNA (AU)

1.09 ± 0.23

1.39 ± 0.44

1.52 ± 0.23

13.02 ± 2.33*

7.47 ± 1.15*^†

9.61 ± 1.07*