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Fig. 1 | Cardiovascular Diabetology

Fig. 1

From: Actions of metformin and statins on lipid and glucose metabolism and possible benefit of combination therapy

Fig. 1

Summary of the effects of metformin on intestinal lipoprotein synthesis in different experimental studies. Key events are the positive regulation of AMPK and GLP-1, from where a spectrum of changes in the fatty acid and TG synthesis, and chylomicron production are observed that effectively result in decreased intestinal lipoprotein synthesis. Arrows represent stimulation, and T-shaped symbols represent inhibition

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