Fig. 1From: Actions of metformin and statins on lipid and glucose metabolism and possible benefit of combination therapySummary of the effects of metformin on intestinal lipoprotein synthesis in different experimental studies. Key events are the positive regulation of AMPK and GLP-1, from where a spectrum of changes in the fatty acid and TG synthesis, and chylomicron production are observed that effectively result in decreased intestinal lipoprotein synthesis. Arrows represent stimulation, and T-shaped symbols represent inhibitionBack to article page