Associations between circulating full-length angiopoietin-like protein 8 levels and severity of coronary artery disease in Chinese non-diabetic patients: a case–control study

Table 4 Multivariate linear regression analyses of circulating full-length ANGPTL8 levels and the Gensini score

	Unadjusted		Model 1		Model 2		Model 3
	Β (95% CI)	P value	Β (95% CI)	P value	Β (95% CI)	P value	Β (95% CI)	P value
ANGPTL8 (per 100 pg increase)	4.641 (1.221–8.060)	0.008*	5.142 (1.300–8.984)	0.009*	5.648 (1.754–9.541)	0.005*	5.701 (1.306–10.096)	0.012*

Model 1: adjusted for age, sex, BMI, and smoker
Model 2: adjusted for Model 1 + SBP, DBP, TG, TC, LDL-C, HDL-C, and non-HDL-C
Model 3: adjusted for Model 2 + ALT and CR
ANGPTL8 angiopoietin-like protein 8, CAD coronary artery disease, BMI body mass index, SBP systolic blood pressure, DBP diastolic blood pressure, TG triglycerides, TC total cholesterol, LDL-C low-density lipoprotein cholesterol, HDL-C high-density lipoprotein cholesterol, ALT alanine aminotransferase, CR creatinine
* P < 0.05, ** P < 0.001

ISSN: 1475-2840