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Table 1 Diabetic (n = 7) and non-diabetic (n = 7) patient characteristics and echocardiographic data

From: Inhibition of calcium/calmodulin-dependent kinase II restores contraction and relaxation in isolated cardiac muscle from type 2 diabetic rats

Parameter

Non-diabetic patient

Type 2 diabetic patient

p-value

Age (years)

68.0 ± 2.0

65.2 ± 2.6

0.41

Sex

6 M, 1 F

6 M, 1 F

n/a

BMI

28.3 ± 1.6

32.6 ± 2.4

0.14

HbA1C (%)

5.4 ± 0.2

7.4 ± 0.5

0.01*

HbA1C (mmol/mol)

36 ± 2

58 ± 6

 

Glucose (mmol/L)

5.9 ± 0.3

8.1 ± 1.6

0.20

Duration of diabetes (y)

12.2 ± 2.3

n/a

n/a

MAP (mmHg)

98.4 ± 5.3

n/a

0.91

Beta blockers

4/7

6/7

n/a

ACE inhibitors

6/7

5/7

n/a

LVEDV (mL)

88 ± 12

86 ± 8

0.89

LVESV (mL)

36 ± 6

35 ± 4

0.92

EF (%)

60 ± 2

60 ± 1

0.86

E vel (cm/s)

0.6 ± 0.1

0.7 ± 0.1

0.56

A vel (cm/s)

0.8 ± 0.1

0.9 ± 0.1

0.26

E/A

0.9 ± 0.1

0.8 ± 0.1

0.50

  1. Data are expressed ± SEM
  2. M male, F female, HbA1C glycated haemoglobin, MAP mean arterial blood pressure, LVEDV left ventricular end diastolic diameter, LVESV left ventricular end systolic diameter, EF ejection fraction
  3. For all parameters independent t-test, * p < 0.05