Skip to main content

Advertisement

Fig. 7 | Cardiovascular Diabetology

Fig. 7

From: Inhibition of calcium/calmodulin-dependent kinase II restores contraction and relaxation in isolated cardiac muscle from type 2 diabetic rats

Fig. 7

Sarcoplasmic reticulum (SR) content is not effected by diabetes or CaMKIIδ inhibition. a, b Representative normalized sarcoplasmic reticulum Ca2+ in nDM and DM KN92 (black line) and nDM KN93 (red line) treated cells. c Mean SR content assessed by 10 mmol/L caffeine-induced fluorescence change (Δ/F0) in nDM and DM KN92 and KN93 treated cells. d, e Representative normalized sarcoplasmic reticulum Ca2+ in nDM and DM control (black line) and AIP (blue line) treated cells. f Mean SR content assessed by 10 mmol/L caffeine-induced fluorescence change (Δ/F0) in nDM and DM control and AIP treated cells. Data are mean ± SEM. n = 11–17 cells. For all parameters two-way between groups ANOVA, p  ≤.05 was used

Back to article page