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Fig. 3 | Cardiovascular Diabetology

Fig. 3

From: Inhibition of calcium/calmodulin-dependent kinase II restores contraction and relaxation in isolated cardiac muscle from type 2 diabetic rats

Fig. 3

Developed force (Fdev) at 2 Hz stimulation frequency is reduced in trabeculae from DM rats compared to nDM controls for trabeculae from nDM to DM rats. This effect is ablated by CaMKII inhibition via KN93 (a) or AIP (b). Data are mean ± SEM. n = 8–10 muscles per group. *p < 0.05 for comparison vs nDM KN92 (a) or nDM Control (b), two-way ANOVA

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