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Fig. 1 | Cardiovascular Diabetology

Fig. 1

From: Inhibition of calcium/calmodulin-dependent kinase II restores contraction and relaxation in isolated cardiac muscle from type 2 diabetic rats

Fig. 1

CaMKIIδ activation is increased in the right atrial appendage tissue from type 2 diabetic patients compared to non-diabetic patients. a Representative immunoblot of total CaMKIIδ, Thr287 phosphorylated (PCaMKIIδ) and GAPDH as a loading control in non-diabetic patients, and type 2 diabetic patients. b Quantification of total CaMKIIδ levels in non-diabetic patients (nDM) (n = 7) and type 2 diabetic patients (DM) (n = 7). c Quantification of PCaMKIIδ levels in non-diabetic patients (nDM) (n = 7) and type 2 diabetic patients (DM) (n = 7). d Quantification of O-GlcNAc modified CaMKIIδ levels in non-diabetic nDM and DM patients (DM) (n = 5). Data are mean ± SEM. *p < 0.05 for comparison of nDM and D values (unpaired t-test)

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