Skip to main content

Table 2 Hazard ratios for CVD and non-CVD mortality in women and men stratified by BMI categories

From: Sex-specific associations between adolescent categories of BMI with cardiovascular and non-cardiovascular mortality in midlife

 

BMI (kg/m2)

Total or BMI as a continuous variable

< 18.5

18.50–21.99

22.0–24.99

25.0–29.99

≥ 30.0

Women

N of participants

128,876

448,712

224,937

99,867

25,476

927,868

Median follow-up (25th; 75th)

16.4 (10.0, 25.6)

18.0 (9.7, 27.9)

17.9 (9.6, 27.9)

15.9 (8.3, 24.8)

11.9 (6.0, 19.5)

17.4 (9.3, 27.0)

Cumulative follow-up (person-years)

2,301,449

8,641,690

4,305,855

1,745,031

352,203

17,346,230

Cardiovascular mortality (451 deaths)

N of deaths

31

189

134

76

21

451

Crude incidence (per 105 person years)

1.34

2.18

3.11

4.35

5.96

2.59

HR

0.68

1 (ref)

1.42

2.13

3.90

1.12 3

95% CI

0.46–0.98

1.14–1.77

1.63–2.78

2.47–6.14

1.096–1.151

p

0.043

0.002

2.9*10−8

4.4*10−9

3.3*10−20

Non-cardiovascular mortality (6235 deaths)

N of deaths

741

3008

1621

707

158

6235

Crude incidence

32.19

34.80

37.64

40.51

44.86

35.94

HR

1.01

1 (ref)

1.07

1.23

1.66

1.031

95% CI

0.93–1.10

1.01–1.14

1.13–1.33

1.42–1.95

1.02–1.04

P

0.80

0.021

10−6

5.3*10−10

4.8*10−14

Men

N of participants

186,190

678,005

324,665

139,556

37,855

1,366,271

Median follow-up (25th; 75th)

19.4 (10.9, 29.8)

20.4 (11.3, 31.9)

19.3 (10.1, 31.1)

16.1 (8.1, 26.9)

11.5 (5.9, 20.1)

19.4 (10.4, 30.8)

Cumulative follow-up (person-years)

3,834,407

14,685,322

6,744,963

2,555,251

547,485

28,367,431

Cardiovascular mortality (3208 deaths)

N of deaths

306

1284

865

578

175

3208

Crude incidence (per 105 person years)

7.98

8.74

12.82

22.62

31.96

11.30

HR

0.99

1 (ref)

1.53

2.99

5.40

1.14

95% CI

0.88–1.13

1.40–1.67

2.71–3.31

4.60–6.33

1.13–1.15

p

0.93

8.7*10−22

10−103

1.8*10−95

3.7*10−169

Non-cardiovascular mortality (22,233 deaths)

N of deaths

2970

11,184

5358

2158

563

22,233

Crude incidence (per 105 person years)

77.45

76.15

79.43

84.45

102.83

78.37

HR

1.04

1 (ref)

1.06

1.16

1.48

1.019

95% CI

1.00–1.09

1.03–1.10

1.11–1.21

1.36–1.61

1.01–1.02

p

0.040

0.0003

6.1*10−10

1.8*10−19

2.6*10−17

  1. The association was assessed with Cox models adjusted for age, sex, birth year, residential socio-economic status, education, country of origin, and height