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Table 2 Multivariable Cox regression analyses for the composite endpoint of all-cause mortality and readmission due to heart failure

From: Prognostic value of the Stanniocalcin-2/PAPP-A/IGFBP-4 axis in ST-segment elevation myocardial infarction

  HR (95% CI) p value
Composite endpoint
 Stanniocalcin-2a 2.06 (1.13–3.75) 0.018
 IGFBP-4a 1.73 (1.14–2.64) 0.010
 Killip–Kimball class III–IV 1.40 (1.13–1.74) 0.002
 NT-ProBNPa 1.21 (1.07–1.37) 0.002
 Age 1.06 (1.04–1.08) < 0.001
 LVEF 0.97 (0.95–0.98) < 0.001
All-cause mortality
 Stanniocalcin-2a 2.23 (1.16–4.29) 0.017
 Killip–Kimball class II–IV 1.64 (1.30–2.08) < 0.001
 NT-ProBNPa 1.18 (1.02–1.36) 0.028
 Age 1.07 (1.05–1.10) < 0.001
 LVEF 0.97 (0.95–0.99) 0.002
Readmission due to heart failure
 Stanniocalcin-2a 3.42 (1.22–9.60) 0.020
 Prior myocardial infarction 2.85 (1.32–6.16) 0.008
 Diabetes mellitus 2.36 (1.22–4.58) 0.011
 Female sex 2.21 (1.15–4.28) 0.018
 Age 1.04 (1.01–1.07) 0.005
 LVEF 0.94 (0.92–0.97) < 0.001
  1. IGFBP-4 insulin-like growth factor binding protein-4, LVEF left ventricular ejection fraction
  2. aHRs (95% CIs) are reported per 1-SD increment of natural log-transformed plasma levels