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Table 2 Multivariable Cox regression analyses for the composite endpoint of all-cause mortality and readmission due to heart failure

From: Prognostic value of the Stanniocalcin-2/PAPP-A/IGFBP-4 axis in ST-segment elevation myocardial infarction

 

HR (95% CI)

p value

Composite endpoint

 Stanniocalcin-2a

2.06 (1.13–3.75)

0.018

 IGFBP-4a

1.73 (1.14–2.64)

0.010

 Killip–Kimball class III–IV

1.40 (1.13–1.74)

0.002

 NT-ProBNPa

1.21 (1.07–1.37)

0.002

 Age

1.06 (1.04–1.08)

< 0.001

 LVEF

0.97 (0.95–0.98)

< 0.001

All-cause mortality

 Stanniocalcin-2a

2.23 (1.16–4.29)

0.017

 Killip–Kimball class II–IV

1.64 (1.30–2.08)

< 0.001

 NT-ProBNPa

1.18 (1.02–1.36)

0.028

 Age

1.07 (1.05–1.10)

< 0.001

 LVEF

0.97 (0.95–0.99)

0.002

Readmission due to heart failure

 Stanniocalcin-2a

3.42 (1.22–9.60)

0.020

 Prior myocardial infarction

2.85 (1.32–6.16)

0.008

 Diabetes mellitus

2.36 (1.22–4.58)

0.011

 Female sex

2.21 (1.15–4.28)

0.018

 Age

1.04 (1.01–1.07)

0.005

 LVEF

0.94 (0.92–0.97)

< 0.001

  1. IGFBP-4 insulin-like growth factor binding protein-4, LVEF left ventricular ejection fraction
  2. aHRs (95% CIs) are reported per 1-SD increment of natural log-transformed plasma levels