Fig. 5

Microbiota characteristics of beta- and alpha-diversity after 8 weeks of treatment with dapagliflozin. a PCoA of OTU-level Bray–Curtis; b hierarchical clustering of OTU-level Bray–Curtis distances using Ward’s linkage; c Chao1 richness estimates; and d Shannon diversity measure of fecal samples across treatment groups OTU. Box represents 25th–75th percentiles, median values are represented by boxplot internal line and ranges by whiskers; ^#p < 0.05 vs both Con groups; n = 6–10/group