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Fig. 3 | Cardiovascular Diabetology

Fig. 3

From: The effect of DPP-4 inhibition to improve functional outcome after stroke is mediated by the SDF-1α/CXCR4 pathway

Fig. 3

Effect of AMD3100 and linagliptin on motor function and tissue damage after MCAO. a Forepaw grip strength at Day 3 after MCAO. b Ischemic volume at Day 3 after MCAO. The number of surviving neurons in the striatum (c) and cortex (d) at Day 3 after MCAO. e Representative photomicrographs of brain sections (NeuN immunostained) used in the quantitative analyses. Solid black line denotes the area of the stroke infarct volume measurement. Solid white line denotes the area of decreased neuronal density after MCAO. Dashed black line denotes the area of neuronal quantification by stereology methods. One-Way ANOVA followed Holm–Sidak’s multiple comparisons test, mean ± SD. * and ** denote p < 0.05 and p < 0.01 respectively and indicate the statistically significant difference over the vehicle group

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Cardiovascular Diabetology

ISSN: 1475-2840