Table 1 Baseline characteristics of the study participants
Variable | Liraglutide (n = 30) | Metformin (n = 30) | P-value |
|---|---|---|---|
Age (years) | 32.67 ± 5.46 | 35.27 ± 5.85 | 0.219 |
Male/female (n) | 20/10 | 20/10 | 1.000 |
BW (kg) | 81 ± 17 | 72 ± 11 | 0.104 |
BMI (kg/m2) | 28.63 ± 3.86 | 26.16 ± 3.1 | 0.063 |
Waist circumference (cm) | 92.20 ± 11.99 | 88.27 ± 8.22 | 0.304 |
Hip circumference (cm) | 99.87 ± 6.02 | 96.33 ± 5.77 | 0.112 |
SBP (mmHg) | 122 ± 16 | 120 ± 11 | 0.643 |
DBP (mmHg) | 79 ± 12 | 81 ± 7 | 0.719 |
Cholesterol (mmol/L) | |||
 Fasting value | 4.79 ± 0.87 | 5.02 ± 0.79 | 0.444 |
 120 min value | 4.45 ± 1.02 | 4.55 ± 0.81 | 0.777 |
Triglycerides (mmol/L) | |||
 Fasting value | 1.82 ± 0.74 | 1.99 ± 0.74 | 0.539 |
 120 min value | 2.07 ± 1.23 | 1.97 ± 0.68 | 0.802 |
LDL-C (mmol/L) | |||
 Fasting value | 3.61 ± 0.82 | 3.78 ± 0.68 | 0.535 |
 120 min value | 3.16 ± 0.70 | 3.28 ± 0.70 | 0.639 |
HDL-C (mmol/L) | |||
 Fasting value | 1.12 ± 0.29 | 1.20 ± 0.26 | 0.448 |
 120 min value | 1.04 ± 0.35 | 1.07 ± 0.23 | 0.793 |
 HbA1c (%) | 8.49 ± 1.81 | 7.77 ± 1.44 | 0.238 |
 FPG (mmol/L) | 9.40 ± 2.32 | 8.45 ± 1.57 | 0.198 |
 30 min PG (mmol/L) | 15.43 ± 2.96 | 13.03 ± 2.72 | 0.028 |
 60 min PG (mmol/L) | 18.19 ± 3.60 | 16.43 ± 4.13 | 0.224 |
 120 min PG (mmol/L) | 17.68 ± 4.38 | 14.47 ± 5.05 | 0.074 |
 Fasting insulin (mIU/L) | 104 (51, 123) | 76 (60, 150) | 0.724 |
 30 min insulin (mIU/L) | 271 (136, 298) | 211 (118, 444) | 0.917 |
 60 min insulin (mIU/L) | 326 (165, 441) | 368 (242, 731) | 0.152 |
 120 min insulin (mIU/L) | 401 (193, 560) | 475 (286, 1060) | 0.178 |
 AUCins (mIU/L) | 648 (321, 742) | 615 (381, 1167) | 0.520 |
 ΔI30/ΔG30 | 24.94 (7.78, 38.89) | 30.18 (10.4, 53.75) | 0.272 |
NEFA (μmol/L) | |||
 Fasting value | 620 ± 468 | 485 ± 225 | 0.325 |
 120 min value | 155 ± 125 | 101 ± 53 | 0.309 |
 sVCAM-1 (ng/ml) | 465 ± 136 | 485 ± 122 | 0.669 |
 sICAM-1 (ng/ml) | 113 ± 40 | 168 ± 110 | 0.085 |
 PAI-1 (ng/ml) | 69.52  ± 45.75 | 51.34  ± 38.87 | 0.227 |