Fig. 2

Change in biomarkers for UC group. Bars indicate UC group mean percent change in biomarkers based on the intention-to-treat analysis with missing values imputed. Percent change is computed as the change in mean values from baseline to 1 year divided by the mean baseline value. Percent change = 100 × [(1 year value − baseline value)/(baseline value)]. Negative values indicate a decrease from baseline to 1 year while positive values indicate an increase. (None of the within group changes were statistically significant, i.e. all P > 0.0019, P adjusted for multiple comparisons.) Error bars represent ± SE. SE as Percent = 100 × [(1 year value SE)/(baseline value)]