Table 2 Subgroup analysis of the associations between change in fasting glucose and the risk of myocardial infarction
Fasting glucose level at baseline (mg/dL) | NFG (< 100.0 mg/dL) | IFG (100.0–125.9 mg/dL) | ||||
|---|---|---|---|---|---|---|
Fasting glucose level after 2-year (mg/dL) | NFG (< 100.0 mg/dL) | IFG (100.0–125.9 mg/dL) | DFG (≥ 126.0 mg/dL) | NFG (< 100.0 mg/dL) | IFG (100.0–125.9 mg/dL) | DFG (≥ 126.0 mg/dL) |
Age < 65 years | ||||||
 Subtotal (N) | 136,764 | 32,057 | 3188 | 28,272 | 19,977 | 3615 |
 Number of cases (n) | 482 | 151 | 15 | 124 | 92 | 31 |
 HR (95% CI) | 1 | 1.06 (0.88–1.28) | 0.85 (0.51–1.42) | 1.15 (0.88–1.51) | 1 | 1.49 (0.98–2.25) |
Age ≥ 65 years | ||||||
 Subtotal (N) | 19,957 | 5765 | 829 | 5335 | 3879 | 849 |
 Number of cases (n) | 199 | 74 | 12 | 65 | 51 | 22 |
 HR (95% CI) | 1 | 1.23 (0.94–1.61) | 1.26 (0.69–2.32) | 0.93 (0.64–1.34) | 1 | 2.02 (1.21–3.35) |
Men | ||||||
 Subtotal (N) | 83,348 | 23,763 | 2790 | 20,418 | 16,354 | 3240 |
 Number of cases (n) | 539 | 183 | 20 | 147 | 120 | 43 |
 HR (95% CI) | 1 | 1.10 (0.93–1.31) | 0.92 (0.58–1.43) | 1.04 (0.81–1.32) | 1 | 1.57 (1.10–2.23) |
Women | ||||||
 Subtotal (N) | 73,373 | 14,059 | 1227 | 13,189 | 7502 | 1224 |
 Number of cases (n) | 142 | 42 | 7 | 42 | 23 | 10 |
 HR (95% CI) | 1 | 1.11 (0.78–1.57) | 1.25 (0.55–2.85) | 1.16 (0.69–1.95) | 1 | 2.11 (0.99–4.47) |
BMI < 25.0 kg/m2 | ||||||
 Subtotal (N) | 111,438 | 24,195 | 2411 | 22,436 | 14,195 | 2368 |
 Number of cases (n) | 439 | 138 | 15 | 112 | 81 | 27 |
 HR (95% CI) | 1 | 1.14 (0.94–1.38) | 0.91 (0.54–1.56) | 0.98 (0.74–1.31) | 1 | 1.71 (1.10–2.65) |
BMI ≥ 25.0 kg/m2 | ||||||
 Subtotal (N) | 45,255 | 13,615 | 1605 | 11,157 | 9651 | 2095 |
 Number of cases (n) | 242 | 87 | 12 | 77 | 62 | 26 |
 HR (95% CI) | 1 | 1.05 (0.82–1.35) | 1.10 (0.62–1.98) | 1.19 (0.85–1.67) | 1 | 1.63 (1.02–2.60) |