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Table 2 Proportion and odds ratios (ORs) of DPN according to CV-HbA1c tertiles (95% CI)

From: HbA1c variability and diabetic peripheral neuropathy in type 2 diabetic patients

 

CV-HbA1c tertiles

p for trend

T1 (≤ 12.9%)

T2 (13.0%–15.7%)

T3 (≥ 15.8%)

n

189

188

186

DPN, n (%)

13 (6.9)

36 (19.1)

53 (28.5)

< 0.001

Model 1

1-reference

3.21 (1.64–6.27)

5.40 (2.83–10.30)

< 0.001

Model 2

1-reference

3.11 (1.57–6.16)

5.38 (2.80–10.35)

< 0.001

Model 3

1-reference

3.33 (1.65–6.73)

6.78 (3.33–13.81)

< 0.001

Model 4

1-reference

3.60 (1.64–7.91)

6.35 (2.83–14.19)

< 0.001

Model 5

1-reference

3.61 (1.62–8.04)

6.48 (2.86–14.72)

< 0.001

  1. Model 1: unadjusted model
  2. Model 2: adjusted for age, female ratio, body mass index, systolic/diastolic BP
  3. Model 3: additionally adjusted for diabetic duration, smoking, drinking, statins medications, hypertension and hypoglycaemia
  4. Model 4: additionally adjusted for serum uric acid, lipid profile, HOMA-IR, initial HbA1c, M-HbA1c and UACR
  5. Model 5: additionally adjusted for hypoglycemic treatments