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Table 2 Proportion and odds ratios (ORs) of DPN according to CV-HbA1c tertiles (95% CI)

From: HbA1c variability and diabetic peripheral neuropathy in type 2 diabetic patients

  CV-HbA1c tertiles p for trend
T1 (≤ 12.9%) T2 (13.0%–15.7%) T3 (≥ 15.8%)
n 189 188 186
DPN, n (%) 13 (6.9) 36 (19.1) 53 (28.5) < 0.001
Model 1 1-reference 3.21 (1.64–6.27) 5.40 (2.83–10.30) < 0.001
Model 2 1-reference 3.11 (1.57–6.16) 5.38 (2.80–10.35) < 0.001
Model 3 1-reference 3.33 (1.65–6.73) 6.78 (3.33–13.81) < 0.001
Model 4 1-reference 3.60 (1.64–7.91) 6.35 (2.83–14.19) < 0.001
Model 5 1-reference 3.61 (1.62–8.04) 6.48 (2.86–14.72) < 0.001
  1. Model 1: unadjusted model
  2. Model 2: adjusted for age, female ratio, body mass index, systolic/diastolic BP
  3. Model 3: additionally adjusted for diabetic duration, smoking, drinking, statins medications, hypertension and hypoglycaemia
  4. Model 4: additionally adjusted for serum uric acid, lipid profile, HOMA-IR, initial HbA1c, M-HbA1c and UACR
  5. Model 5: additionally adjusted for hypoglycemic treatments