| |
T1DM
|
T2DM
|
|---|
|
T1DM (n = 20)
|
Control to T1DM (n = 10)
|
P
|
T2DM (n = 20)
|
Control to T2DM (n = 10)
|
P
|
|---|
|
LVMI (g/m2)
|
78 ± 8
|
83 ± 13
|
0.19
|
78 ± 9
|
68 ± 18
|
0.07
|
|
RWT
|
0.38 ± 0.07
|
0.35 ± 0.06
|
0.35
|
0.44 ± 0.07
|
0.36 ± 0.05
|
0.002
|
|
LVEDVI (ml/m2)
|
50 ± 13
|
56 ± 19
|
0.28
|
42 ± 10
|
54 ± 13
|
0.008
|
|
LVEF (%)
|
60 ± 4
|
60 ± 5
|
0.93
|
59 ± 6
|
59 ± 5
|
0.91
|
|
LVs’ (cm/s)
|
6.5 ± 0.9
|
7.1 ± 1.1
|
0.11
|
5.8 ± 1.2
|
5.7 ± 1.0
|
0.76
|
|
LV GLS (%)
|
− 18.9 ± 2.4
|
− 19.9 ± 2.0
|
0.29
|
− 18.1 ± 2.1
|
− 19.8 ± 2.4
|
0.055
|
|
LV strain rate
|
− 1.1 ± 0.2
|
− 1.1 ± 0.1
|
0.45
|
− 1.1 ± 0.2
|
− 1.1 ± 0.2
|
0.93
|
|
LAVI (ml/m2)
|
34 ± 11
|
41 ± 10
|
0.13
|
33 ± 6
|
39 ± 7
|
0.03
|
|
RVs’ (cm/s)
|
10.5 ± 1.7
|
11.1 ± 1.5
|
0.33
|
10.0 ± 1.7
|
10.3 ± 1.2
|
0.56
|
|
RVFAC (%)
|
49 ± 5
|
46 ± 7
|
0.32
|
42 ± 4
|
45 ± 6
|
0.18
|
|
RV GLS (%)
|
− 29.2 ± 5.8
|
− 27.0 ± 4.3
|
0.31
|
− 24.9 ± 4.6
|
− 20.4 ± 13.4
|
0.19
|
|
PASP (mmHg)
|
24 ± 5
|
26 ± 4
|
0.45
|
29 ± 6
|
27 ± 4
|
0.33
|
|
E (m/s)
|
0.81 ± 0.16
|
0.77 ± 0.19
|
0.50
|
0.72 ± 0.13
|
0.66 ± 0.24
|
0.38
|
|
A (m/s)
|
0.49 ± 0.18
|
0.46 ± 0.12
|
0.63
|
0.66 ± 0.15
|
0.45 ± 0.11
|
0.001
|
|
E/A
|
1.8 ± 0.6
|
1.7 ± 0.6
|
0.77
|
1.1 ± 0.3
|
1.6 ± 0.9
|
0.046
|
|
DT (ms)
|
189 ± 22
|
192 ± 25
|
0.70
|
199 ± 28
|
200 ± 21
|
0.95
|
|
e’sep (cm/s)
|
9.2 ± 1.8
|
9.3 ± 1.8
|
0.85
|
5.8 ± 1.6
|
6.9 ± 2.0
|
0.13
|
|
E/e’sep (rest)
|
9 ± 3
|
9 ± 3
|
0.60
|
13 ± 4
|
10 ± 2
|
0.02
|
|
E/e’sep (peak)
|
9 ± 2
|
8 ± 4
|
0.37
|
11 ± 2
|
10 ± 2
|
0.16
|
- Statistically significant differences are highlighted in italic
- LVMI left ventricular mass index, RWT relative wall thickness, LVEDVI left ventricular end diastolic volume index, LVEF left ventricular ejection fraction, LVs’ LV tissue Doppler septal peak systolic velocity, LV GLS left ventricular global longitudinal strain, LAVI left atrial volume index, RVs’ RV tissue Doppler free wall peak systolic velocity, RVFAC right ventricular fractional area change, RV GLS RV global longitudinal strain, PASP pulmonary artery systolic pressure, E early mitral inflow velocity, A late mitral inflow velocity, DT deceleration time, e’
sep
tissue Doppler septal mitral annular early diastolic velocity, E/e’
sep
ratio of early mitral inflow velocity to tissue Doppler septal mitral annular early diastolic velocity
