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Table 1 Event rates of CVD in PCOS OUH, PCOS Denmark and controls

From: Cardiovascular disease in a nationwide population of Danish women with polycystic ovary syndrome

  PCOS OUH (N = 1159) PCOS Denmark (N = 17,995) Controls (N = 52,329) Pa Pb
N (%) IR N (%) IR N (%) IR
CVD events 264 (23) 22.6 3970 (22) 22.0 7344 (14) 13.2 < 0.001 0.54
CVD (HT and DL excluded) 71 (6) 5.4 1290 (7) 6.4 2678 (5) 4.5 < 0.001 0.16
ICD10 CVD, total 121 (10) 9.5 1727 (10) 8.7 3089 (6) 5.2 < 0.001 0.31
E 78 (dyslipidemia) 33 (3) 2.5 431 (2) 2.1 653 (1) 1.1 < 0.001 0.30
G45–46, I63–66 (TCI, stroke) 16 (1) 1.2 206 (1) 1.0 524 (1) 0.9 0.102 0.44
I10–13 (hypertension) 77 (7) 5.9 1004 (6) 4.9 1484 (3) 2.5 < 0.001 0.10
I20–25 (CVD) 20 (2) 1.5 364 (2) 1.8 854 (2) 1.4 0.001 0.46
I26 (VTE lung) 4 (0.4) 0.3 97 (0.5) 0.5 151 (0.3) 0.2 < 0.001 0.35
I50 (incompensatio) 0 Na 47 (0.3) 0.2 200 (0.4) 0.3 0.018 0.07
I80–82 (VTE extremities) 17 (1) 1.3 216 (1) 1.0 451 (1) 0.7 < 0.001 0.39
Medical treatment 247 (21) 20.8 3643 (20) 20.0 6656 (13) 11.9 < 0.001 0.35
Antithrombotics (B01) 50 (4) 3.8 940 (5) 4.6 1887 (4) 3.2 < 0.001 0.15
Antihypertensive (C02, C07–09) 189 (16) 15.4 2744 (15) 14.5 5087 (10) 8.9 < 0.001 0.30
Antilipids (C10) 121 (10) 9.4 1601 (9) 8.1 2833 (5) 4.8 < 0.001 0.06
  1. IR: incidence rate. Presented per 1000 PY (person years)
  2. VTE: venous thromboembolism
  3. HT: hypertension defined as ICD10 codes I10–13 OR prescription of C02, C07–09 (two or more medicine withdrawals within the same ATC group 3 months or later after the index date)
  4. DL: dyslipidemia defined as (ICD 10 code) E78 OR prescription of C10 (two or more medicine withdrawals within the same ATC group 3 months or later after the index date)
  5. Pa: Chi square test between PCOS Denmark and controls
  6. Pb: Chi square test between PCOS OUH and controls