Fig. 6
From: MicroRNA-19a contributes to the epigenetic regulation of tissue factor in diabetes
miR-19a and miR-126 cooperatively supress the TF 3′UTR. Hek cells were co transfected with a TF-3′UTR-harbouring reporter plasmid and a control miR, miR-19a, miR-126, or miR-19a and miR-126 together. After 24 h (a) the firefly luciferase activity was measured and normalized to renilla luciferase activity. b Illustration of the predicted binding sites for miR-19a and miR-126 within the 3′UTR of the TF transcript using the online software RNAfold (http://rna.tbi.univie.ac.at/cgi-bin/RNAWebSuite/RNAfold.cgi). Data are represented as mean ± SEM. **p < 0.01, n ≥ 4