Fig. 4
From: MicroRNA-19a contributes to the epigenetic regulation of tissue factor in diabetes
miR-19a reduces TF procoagulant activity in human monocytic cells miR-19a expression in THP-1 cells stimulated with 10 μg/mL LPS for 2 or 4 h (a). THP-1 cells were transfected with either a control mimic or miR-19 as well as an inhibitor control or anti-miR-19a. 24 h post transfection cells were stimulated with 10 μg/mL LPS and TF mRNA and TF activity assessed by real-time PCR and a FXa chromogenic assay, respectively. b, e asTF and c, f flTF mRNA 2 h following stimulation with LPS. d, g TF activity 6 h post stimulation with LPS. Data are represented as mean ± SEM. *p < 0.05, **p < 0.01, ***p < 0.001, n ≥ 4