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Fig. 3 | Cardiovascular Diabetology

Fig. 3

From: Potential role of insulin receptor isoforms and IGF receptors in plaque instability of human and experimental atherosclerosis

Fig. 3

IR, IGF-IR and IGF-IIR expression in aorta from the 24-week-old model of experimental atherosclerosis. Representative photomicrographs and quantifications of immunohistochemistry against IR (a), IGF-IR (c) or IGF-IIR (e) in aortic roots from 24-week-old Control, ApoE−/− and BATIRKO; ApoE−/− mice. qRT-PCR analysis of IRA and IRB isoforms (b) or IGF-IR (d) expression in aorta from 24-week-old Control, ApoE−/− and BATIRKO; ApoE−/− mice. *p < 0.05, **p < 0.005, ***p < 0.0005 vs. Control mice; †p < 0.05 vs. ApoE−/− mice. C 24 weeks (n = 7); AE 24 weeks (n = 8); B;AE 24 weeks (n = 7). AE ApoE−/−, B;AE BATIRKO; ApoE−/−, C control

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Cardiovascular Diabetology

ISSN: 1475-2840