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Table 3 Serum phospholipid fatty acids composition in the study patients

From: Relationship between polyunsaturated fatty acid composition in serum phospholipids, systemic low-grade inflammation, and glycemic control in patients with type 2 diabetes and atherosclerotic cardiovascular disease

Fatty acid HbA1c < 7.0%
n = 38
HbA1c ≥ 7.0%
n = 36
p value
SFAs
 C12:0 (µmol/l) 1.73 (1.14; 2.84) 2.25 (1.39; 3.31) 0.17
 C14:0 (µmol/l) 16.20 (15.09; 18.12) 18.31 (14.37; 20.92) 0.18
 C16:0 (µmol/l) 940.62 (833.71; 1022.22) 973.60 (868.19; 1074.23) 0.50
 C18:0 (µmol/l) 421.96 ± 92.87 439.14 ± 96.71 0.44
 C24:0 (µmol/l) 24.17 (19.31; 28.40) 24.695 (20.38; 30.34) 0.99
MUFAs
 C16:1 (µmol/l 15.06 (12.33; 21.72) 14.56 (12.00; 19.79) 0.60
 C18:1 (µmol/l) 270.77 (244.27; 332.28) 285.625 (246.25; 336.565) 0.75
n-3 PUFAs
 C18:3; ALA (µmol/l) 5.75 (4.73; 8.48) 7.21 (5.22; 8.94) 0.26
 C20:5; EPA (µmol/l) 71.66 (48.65; 90.31) 48.55 (38.96; 66.86) 0.002
 C22:6; DHA (µmol/l) 303.11 (241.62; 355.04) 263.25 (208.77; 325.18) 0.07
n-6 PUFAs
 C18:2; LA (µmol/l) 421.46 (343.43; 476.27) 471.02 (402.46; 546.30) 0.02
 C20:2 (µmol/l) 16.39 (13.24; 18.33) 18.21 (14.39; 22.26) 0.14
 C20:4; AA (µmol/l) 542.03 ± 95.38 561.92 ± 154.30 0.51
Total SFAs (µmol/l) 1439.66 ± 288.90 1431.66 ± 282.75 0.90
Total MUFAs (µmol/l) 286.15 (260.18; 356.12) 308.95 (261.43; 357.57) 0.77
Total n-3 PUFAs (µmol/l) 378.16 (296.06; 436.75) 320.70 (260.36; 396.61) 0.02
Total n-6 PUFAs (µmol/l) 986.24 ± 171.11 1065.54 ± 210.49 0.08
Total FAs (µmol/l) 3088.55 (2785.20; 3413.38) 3148.76 (2748.18; 3519.32) 0.65
n-6/n-3 ratioa 2.69 ± 0.78 3.32 ± 0.83 0.001
EPA/AA ratio 0.13 (0.07; 0.14) 0.10 (0.07; 0.12) 0.008
DHA/AA ratio 0.13 (0.09; 0.17) 0.50 (0.41; 0.59) 0.15
  1. Data are given as number (percentage) for categorical variables and mean (± standard deviation) or median (IQR) for continuous variables
  2. Italic values indicate significance of p value (p < 0.05)
  3. AA arachidonic acid, ALA alpha-linolenic acid, DHA docosahexaenoic acid, EPA eicosapentaenoic acid, FAs fatty acids, LA linoleic acid, MUFAs monounsaturated fatty acids, PUFAs polyunsaturated fatty acids, SFAs saturated fatty acids
  4. aThe n-6/n-3 fatty acid ratio was calculated by measuring: linoleic, C18:2n-6; eicosadienoic, C20:2n-6; arachidonic, C20:4n-6 acids to estimate total n-6 PUFAs and alpha-linolenic, C18:3n-3; eicosapentaenoic, C20:5n-3; docosahexaenoic, C22:6n-3 acids to estimate the total n-3 PUFAs