Table 2 Baseline laboratory investigations (n = 74)

HbA_1c (%)

7.0 (6.6; 7.5)

6.6 (6.5; 6.8)

7.5 (7.2; 8.3)

Insulin (µIU/ml)

21.5 (14.6; 33.6)

19.1 (14.6; 27. 9)

24.4 (14.8; 38.5)

C-peptide (ng/ml)

3.25 ± 1.40

3.61 ± 1.47

2.87 ± 1.24

TC (mmol/l)

3.86 ± 0.91

3.69 ± 0.85

4.04 ± 0.95

LDL-C (mmol/l)

1.91 (1.53; 2.64)

1.825 (1.45; 2.51)

1.99 (1.63; 2.90)

HDL-C (mmol/l)

1.24 ± 0.38

1.28 ± 0.36

1.21 ± 0.40

Tg (mmol/l)

1.35 (1.12; 1.92)

1.375 (0.99; 1.91)

1.34 (1.14; 1.99)

Creatinine (µmol/l)

83.7 ± 22.0

82.9 ± 17.8

84.5 ± 25.9

eGFR (MDRD) (ml/min/1.73 m²)

78.3 (70.0; 90.0)

81.8 (70.0; 90.0)

78.0 (64.0; 90.0)

hsCRP (mg/l)

1.54 (0.73; 2.71)

1.33 (0.52; 2.43)

1.87 (0.85; 4.39)

IL-6 (pg/ml)

1.99 (1.55; 2.79)

1.88 (1.36; 2.28)

2.17 (1.64; 3.13)

TNFα (pg/ml)

1.48 (1.28; 1.76)

1.43 (1.24; 1.68)

1.52 (1.40; 1.79)